Metal-Free Synthesis of Isothiocyanato Alkyl Sulfides from Alkenes with KSCN and DMTSM DOI

Shixuan Jiang,

Daijiao Zhuang,

Peihua Liu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(22), С. 4472 - 4477

Опубликована: Янв. 1, 2024

A metal-free method to synthesize diversely substituted isothiocyanato alkyl sulfides with KSCN and DMTSM has been developed through the formation of C–NCS C–S bonds.

Язык: Английский

Thiocyanoalkylation of Alkenes via Dual Photoredox and Copper Catalysis DOI
Xu Wang,

Bi-Yin Xiao,

Qin Jiang

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 7, 2024

Organic thiocyanates are commonly used as essential organic synthesis intermediates and widely present in various drug molecules bioactive molecules.

Язык: Английский

Процитировано

2
C‐Centered radical intermediates for C(sp3)‐H bonds functionalization: An emerging approach towards alkyl thiocyanates DOI Creative Commons
Floris Buttard,

Jordan Vigier,

H. Lebel

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(8)

Опубликована: Янв. 8, 2024

Abstract Organic thiocyanates are an important class of compounds because they present in several bioactive molecules and can be used as key synthetic intermediates to access biorelevant sulfur‐containing scaffolds. Although the chemistry organothiocyanates has been studied for decades, a recent resurgence interest field led major advances synthesis new bearing thiocyanate moiety. An emerging powerful strategy consists selective functionalization C(sp 3 )‐H bonds through formation C‐centered radical intermediate. This review highlights work that reported novel alkylthiocyanate scaffolds this promising approach.

Язык: Английский

Процитировано

1
Carbonylative Cyclization of Biaryl Enones with Aldehydes and Oxamic Acids DOI
Chada Raji Reddy, Dattahari H. Kolgave,

Sana Fatima

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(24), С. 4901 - 4911

Опубликована: Янв. 1, 2024

An oxidative radical-promoted carbonylative cyclization strategy for the synthesis of phenanthren-9-(10

Язык: Английский

Процитировано

1
Visible Light-Induced Copper-Catalyzed Regio- and Stereoselective Difluoroalkylthiocyanation of Alkynes DOI

Xiaoxue Hu,

Yanzhao Wang, Shibo Xu

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(12), С. 9118 - 9124

Опубликована: Июнь 6, 2024

The first regio- and stereoselective difluoroalkylthiocyanation of alkynes with BrCF

Язык: Английский

Процитировано

1
Electrophotocatalytic Thiocyanation and Sulfonylation Cyclization of Unactivated Alkenes DOI
Yingchun Ma,

Ping Yu,

Ruoyu Qin

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 18, 2024

We report an electrophotocatalytic process that enables the thiocyanation and sulfonylation/cyclization of alkenes. It is applicable to a wide range unactivated alkenes, using inexpensive photocatalyst 2,4,6-triphenylpyrylium tetrafluoroborate (TPPT) produce diverse array heterocycles containing sulfonyl thiocyano groups with good functional group tolerance. The protocol operates under mild, chemical oxidant- transition-metal-free, broad scope substrates. Preliminary mechanistic studies suggest reaction involves combination electrolysis reductive quenching photocatalytic cycle TPPT.

Язык: Английский

Процитировано

1
Metal-Free Synthesis of Isothiocyanato Alkyl Sulfides from Alkenes with KSCN and DMTSM DOI

Shixuan Jiang,

Daijiao Zhuang,

Peihua Liu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(22), С. 4472 - 4477

Опубликована: Янв. 1, 2024

A metal-free method to synthesize diversely substituted isothiocyanato alkyl sulfides with KSCN and DMTSM has been developed through the formation of C–NCS C–S bonds.

Язык: Английский

Процитировано

0