Pd‐Catalyzed Cyclization of o‐Iodoanilines with Acrylates or Acrylic Acids: A Convenient One‐Step Route to 2‐Quinolinones

European Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Сен. 23, 2024

Abstract A convenient and general method for the construction of 2‐quinolinones was developed in this paper. The Pd‐catalyzed cyclization reaction various o ‐iodoanilines with acrylates or acrylic acids proceeded smoothly to produce 28–>99 % yields. key achieve is utilize suitable base, such as potassium pivalate acetate. Various synthetically useful functional groups, halogen atoms, methoxycarbonyl, nitro remained intact during reaction. effects catalyst base on kinetic experiments were investigated understand aspect

Язык: Английский

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Five-membered ring systems: With more than 1 N atom

Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 211 - 257

Опубликована: Янв. 1, 2024

Язык: Английский

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Site-Specific Dehydrogenative Hydroxyfluoroalkylation of Indoles with Hexafluoroisopropanol

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 22, 2024

An efficient and convenient method for the synthesis of C3-hydroxytrifluoroalkylated indoles pyrroles was described in this paper. The copper-catalyst-free site-specific cross-dehydrogenative coupling reaction various with hexafluoroisopropanol proceeded smoothly by using MnO

Язык: Английский

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