Titanocene dichloride-catalyzed synthesis of heterocycles accelerated by in-situ formed Lewis and Brønsted acids
Molecular Catalysis,
Год журнала:
2025,
Номер
573, С. 114822 - 114822
Опубликована: Янв. 18, 2025
Язык: Английский
The Nazarov Reaction
Emily Schmidt,
Seifeddine Khalifa,
F. G. West
и другие.
Elsevier eBooks,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Recent Developments in Asymmetric Nazarov Reactions
Current Organic Chemistry,
Год журнала:
2024,
Номер
28(10), С. 757 - 776
Опубликована: Апрель 17, 2024
Abstract:
The
Nazarov
reaction
involves
the
cyclization
of
divinyl
ketones
into
cyclopentenones
under
influence
strong
acids.
prevalence
five-membered
carbocycles
in
a
multitude
natural
and
bioactive
products
has
triggered
an
intense
development
efficient
methods
for
their
construction.
In
particular,
asymmetric
versions
are
achieved
by
using
either
chiral
auxiliary
or
catalyst,
which
can
be
organocatalyst,
metal
multicatalytic
system.
This
review
aims
to
update
field
reactions
published
since
2017.
It
is
divided
four
sections,
dealing
successively
with
auxiliaries,
organocatalytic
enantioselective
reactions,
metal/boron-catalyzed
reactions.
Each
section
subdivided
simple
Nazarov-based
domino/tandem
have
allowed
numerous
more
complex
functionalized
molecules
synthesized
one-pot
procedures.
Язык: Английский
Palladium-Catalyzed Synthesis of Indanone via C–H Annulation Reaction of Aldehydes with Norbornenes
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
89(1), С. 784 - 792
Опубликована: Дек. 14, 2023
A
novel
methodology
for
the
synthesis
of
indanone
derivates
has
been
developed.
The
palladium-catalyzed
annulation
reaction
o-bromobenzaldehydes
with
norbornene
derivatives
is
achieved
through
extremely
concise
processes.
skeleton
was
established
directly
via
C–H
activation
aldehyde
group
under
a
mild
condition.
This
method
simple
and
practical,
which
simplified
traditional
rapid
construction
indanone.
Язык: Английский
Switchable Enantioselectivity in Conjugate Alkyne Addition of β,γ-Unsaturated α-Keto Esters by Asymmetric Binary Acid Catalysis
Depeng Duan,
Mengdie Tang,
Man Wang
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(17), С. 3612 - 3616
Опубликована: Апрель 24, 2024
Switchable
enantioselectivity
was
uncovered
in
the
enantioselective
catalytic
conjugate
addition
of
β,γ-unsaturated
α-keto
esters
with
terminal
alkynes
to
chiral
Lewis
acid
complex
In(BF
Язык: Английский
Cu(OTf)2–Phosphoric Acid-Catalyzed Tandem Oxa-Nazarov Cyclization and Dibromination of Conjugated 1,2-Diketones
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(22), С. 15862 - 15870
Опубликована: Ноя. 1, 2023
A
facile
tandem
oxa-Nazarov
cyclization
and
dibromination
has
been
developed.
The
combination
of
Cu(OTf)2
diphenyl
phosphate
(DPP-H)
was
found
to
synergistically
promote
the
coupling
conjugated
1,2-diketones
N-bromosuccinimide
form
2,4-dibromo-3(2H)-furanones
in
good
yields.
Язык: Английский
Rapid Construction of Polycyclic Skeletons via Brønsted-Base-Catalyzed Annulations of Ethylidene 1,3-Indenediones and Vinyl 1,2-Diketones
Organic Letters,
Год журнала:
2024,
Номер
26(28), С. 5893 - 5898
Опубликована: Июль 9, 2024
Brønsted-base-catalyzed
diversified
annulations
between
ethylidene
1,3-indenediones
and
vinyl
1,2-diketones
have
been
achieved,
delivering
three
types
of
products
containing
oxabicyclo[3.2.1]octane,
spiro[4.5]decane,
branched
triquinane
skeletons,
respectively,
which
widely
exist
in
natural
bioactive
substances.
Two
unprecedented
reaction
modes
disclosed,
the
reactions
could
be
readily
scaled
up.
The
protocol
shows
potential
1,2-diketone-mediated
rapid
construction
complicated
polycyclic
scaffolds.
Язык: Английский