Enantioselective Total Synthesis of (+)‐Propolisbenzofuran B† DOI
Wenxiu Xu,

Li‐Han Zhao,

Yao Zhu

и другие.

Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(22), С. 2833 - 2839

Опубликована: Июль 22, 2024

Comprehensive Summary The first catalytic asymmetric total synthesis of (+)‐propolisbenzofuran B, enabled by a highly enantioselective rhodium‐catalyzed hydrogenation tetrasubstituted olefin, was described. Other noteworthy aspects include the construction central hydrodibenzo[ b , d ]furan core through sequence Zn(II)‐mediated regioselective benzofuran formation and Dieckmann condensation, as well C‐H oxidations, involving visible light‐induced Fe(III)‐catalyzed benzylic C(sp 3 )‐H oxidation. Additionally, absolute configuration confirmed X‐ray analysis carbonate intermediate.

Язык: Английский

Recent advances in the metal-catalyzed asymmetric alkene hydrogenation of cyclic conjugated carbonyl compounds DOI
Min Tan, Bram B. C. Peters, Pher G. Andersson

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(10), С. 2934 - 2953

Опубликована: Янв. 1, 2024

This review summarizes the recent advances (2016–2023) in stereoselective metal-catalyzed hydrogenation of cyclic α,β-unsaturated ketones, lactams and lactones since considerable developments were made. Where possible application these methodologies synthesis is outlined.

Язык: Английский

Процитировано

7
Cyclolignan synthesis streamlined by enantioselective hydrogenation of tetrasubstituted olefins DOI
Wenxiu Xu, Zhuo Peng,

Qing‐Xiu Gu

и другие.

Nature Synthesis, Год журнала: 2024, Номер 3(8), С. 986 - 997

Опубликована: Июнь 20, 2024

Язык: Английский

Процитировано

7
Enantioselective total syntheses of (−)-mitragynine, (−)-quinine and (+)-quinidine enabled by Ir-catalysed asymmetric hydrogenation of all-carbon tetrasubstituted cycloalkenes DOI
Kai Zhang,

Peng Cui,

Miao Miao

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(5), С. 1456 - 1461

Опубликована: Янв. 1, 2024

Syntheses of (−)-mitragynine, (−)-quinine and (+)-quinidine are reported based on Ir-catalysed asymmetric hydrogenation tetrasubstituted α-acylpyrazole-β-alkyl cycloalkenes to construct piperidine rings bearing 1,2-contiguous cis -stereocenters in high yields excellent enantioselectivities.

Язык: Английский

Процитировано

2
Asymmetric hydrogenation of tetrasubstituted β-phosphorylated α,β-unsaturated esters catalyzed by nickel complexes of chiral phosphinooxazolines DOI Creative Commons
Zhuo Peng,

Qing‐Xiu Gu,

Yao Zhu

и другие.

Cell Reports Physical Science, Год журнала: 2024, Номер unknown, С. 102261 - 102261

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

1
Enantioselective Total Synthesis of (+)‐Propolisbenzofuran B† DOI
Wenxiu Xu,

Li‐Han Zhao,

Yao Zhu

и другие.

Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(22), С. 2833 - 2839

Опубликована: Июль 22, 2024

Comprehensive Summary The first catalytic asymmetric total synthesis of (+)‐propolisbenzofuran B, enabled by a highly enantioselective rhodium‐catalyzed hydrogenation tetrasubstituted olefin, was described. Other noteworthy aspects include the construction central hydrodibenzo[ b , d ]furan core through sequence Zn(II)‐mediated regioselective benzofuran formation and Dieckmann condensation, as well C‐H oxidations, involving visible light‐induced Fe(III)‐catalyzed benzylic C(sp 3 )‐H oxidation. Additionally, absolute configuration confirmed X‐ray analysis carbonate intermediate.

Язык: Английский

Процитировано

0