Brazilian Journal of Physics, Год журнала: 2023, Номер 54(2)
Опубликована: Дек. 28, 2023
Язык: Английский
Biomaterials Research, Год журнала: 2025, Номер 29
Опубликована: Янв. 1, 2025
Cancer remains a major concern for human health worldwide. To fight the curse of cancer, boron neutron capture therapy is an incredibly advantageous modality in treatment cancer as compared to other radiotherapies. Due tortuous vasculature and around tumor regions, ( 10 B) compounds preferentially house into cells, creating large dose gradient between highly mingled cells normal cells. Epithermal or thermal bombardment leads tumor-cell-selective killing due generation heavy particles yielded from situ fission reaction. However, challenges nanocomposites’ development have been synthesis part well requirement selective targeting delivery therapeutic concentrations with nominal healthy tissue accumulation retention. circumvent above challenges, this review discusses boride nanocomposite design, safety, biocompatibility biomedical applications general public use. This sparks interest using nanocomposites agents repurposing them comorbidity treatments, future scientific opportunities, hope accelerate stimulus developing possible composite nanomedicine research
Язык: Английский
Процитировано
1
Biomass Conversion and Biorefinery, Год журнала: 2023, Номер unknown
Опубликована: Окт. 16, 2023
Abstract Pathogenic microorganisms and cancer continue to be the most difficult problem in public health care incidence of diseases caused by such resistant strains cells are growing. Recent advances nanotechnology open up new possibilities for creating novel, exciting nanoparticles that safe human may used as smart antibacterial anticancer medicines. The novelty present study is extracellular green synthesis zinc oxide (ZnO NPs), gold (Au) NPs using cell filtrate endophytic fungus Fusarium chlamydosporum MW341592.1 isolated from healthy leaves Eucalyptus sideroxylon plant. Eco-friendly synthesized ZnO Au were screening their activity against select carcinomic lines some multidrug-resistant bacteria. characterized UV-Vis. spectroscopy, X-ray diffraction (XRD), dynamic light scattering (DLS), transition electron microscopy (TEM), energy-dispersive spectroscopy (EDX). absorption spectra produced showed bands UV area at 320 nm, whereas region 530 nm. TEM revealed average sizes NPs, 19.3 nm 22.1 respectively, while shape both with spherical-like shape. Biological assay raising NP concentration lowers number HCT-116 colon CACO2 intestinal cells, well associated pathogens Escherichia coli Pseudomonas aeruginosa.
Язык: Английский
Процитировано
14
Biomass Conversion and Biorefinery, Год журнала: 2023, Номер unknown
Опубликована: Окт. 4, 2023
Язык: Английский
Процитировано
13
Scientific Reports, Год журнала: 2023, Номер 13(1)
Опубликована: Дек. 16, 2023
Abstract Plastic is a fossil-based synthetic polymer that has become an essential material in our daily life. pollution resulting from the accumulation of plastic objects problematic for environment. Bioplastic can be biodegradable environmentally friendly alternative plastic. In this paper, bioplastics based on polyvinyl alcohol (PVA)/gellan gum (GG) blend have been produced three different compositions and their chemical structure, mechanical, morphological thermal properties studied. Glycerol used as plasticizer. To add extra features to PVA/GG bioplastic, Psidium guajava (guava) leaves, GL, chickpea, CP, extracts added (30/70) blend. Water aqueous ethanol extraction GL respectively. The addition plant’s enhanced tensile bioplastic. Weathering acceleration tests carried out examine degradation prepared bioplastics. Cytotoxicity studies revealed bioplastic safe food packaging applications. oxygen permeability new also plant (GL CP extracts) increased water extents. life cycle assessment (LCA) CO 2 emissions comparison investigated. From all results, proved degradable, effective plastics
Язык: Английский
Процитировано
11
Bioresources and Bioprocessing, Год журнала: 2025, Номер 12(1)
Опубликована: Апрель 12, 2025
The biosynthesis of bimetallic nanoparticles using plant extracts has garnered significant attention due to their eco-friendly and cost-effective nature. This study aimed biosynthesize magnesium oxide-zinc oxide nanocomposite (MgO-ZnO nanocomposite) Pluchea indica leaf extract for the first time, with a focus on characterizing its physicochemical properties evaluating biological activities. biosynthesized MgO-ZnO was fully characterized, revealing an absorbance peak at 300 nm UV-vis spectroscopy. Transmission electron microscopy (TEM) confirmed particle stability within size range 5-35 nm. Cytotoxicity analysis Wi 38 normal cell line demonstrated IC50 value 179.13 µg/mL, indicating good biosafety. exhibited potent anticancer activity, values 73.61 µg/mL 31.25 against Hep-G2 MCF-7 cancer lines, respectively. Antibacterial assays revealed activity Klebsiella pneumoniae, Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans, minimum inhibitory concentrations (MICs) ranging from 250 µg/mL. Furthermore, displayed antioxidant 175 as determined by DPPH assay. In conclusion, successful synthesis P. demonstrates potential safe effective agent concentration-dependent antioxidants, antibacterial, applications. highlights versatility plant-mediated in developing functional nanomaterials biomedical use.
Язык: Английский
Процитировано
0
Composite Interfaces, Год журнала: 2025, Номер unknown, С. 1 - 22
Опубликована: Май 31, 2025
Язык: Английский
Процитировано
0
Microbial Pathogenesis, Год журнала: 2025, Номер unknown, С. 107783 - 107783
Опубликована: Июнь 1, 2025
Язык: Английский
Процитировано
0
Biomass Conversion and Biorefinery, Год журнала: 2023, Номер unknown
Опубликована: Сен. 30, 2023
Abstract Pythium irregulare ( P. ) is one of the soil-borne pathogens that primary cause damage to several plants each year. The novelty and originality this work were ability Streptomyces gancidicus S. OR229936) synthesize bimetallic zinc oxide-boron oxide nanoparticles (ZnO-B 2 O 3 NPs) for reducing growth safeguarding pea plant from damping off disease. produced ZnO-B NPs’ XRD results highlighted ZnO diffraction peaks at 2Ɵ = 27.50°, 31.15°, 45.15°, 56.89°, 67.98°, 75.25°, which are complemented by standard card JCPDS number 361451 correspond (002), (101), (102), (110), (103), (201) Bragg’s reflections. Along with 300019, they additionally include B NP 15.25°, 28.69°, 31.99°, 41.28°. Bimetallic NPs tested against irregular their antifungal activities. findings indicated exhibited potential anti activity, an inhibition zone 33 mm a concentration 1000 µg/mL promising MIC 0.01 µg/mL. (0.01 ppm) application appeared significantly lessen severity post-emergence damaging disease 10% provide significant protection 88%. In comparison fungicide (difenoconazole 25%) treatments, all metabolic resistance indicators enhanced after usage NPs, ethyl acetate extract . beneficial impacts have been broadened increase enzyme activities peroxidase (POD) polyphenol oxidase (PPO) in both healthy infected control. Reduction Malondialdehyde content (MDA) response gancidius filtrate, difenoconazole 41.68%, 36.51%, 26.15, 15.25%, respectively. Also, contents H diminished 50%, 45%, 40%, 37.5%, 22.5% difenoconazole, comparing -infected strong evidence induce recovery. seems be approach relieve toxic influences on as green alternative therapeutic nutrients chemical fungicides.
Язык: Английский
Процитировано
8
Materials Today Communications, Год журнала: 2024, Номер 41, С. 110644 - 110644
Опубликована: Окт. 9, 2024
Язык: Английский
Процитировано
2
Journal of Molecular Structure, Год журнала: 2024, Номер unknown, С. 140945 - 140945
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
2