Biosynthesis of Zinc Oxide Nanoparticles Using Seaweed: Exploring Their Therapeutic Potentials

Applied Sciences, Год журнала: 2024, Номер 14(16), С. 7069 - 7069

Опубликована: Авг. 12, 2024

This study aimed to biosynthesize zinc oxide nanoparticles (ZnO-NPs) using extracts from various seaweeds, including Ulva lactuca, intestinalis (Chlorophyta), and Sargassum muticum (Phaeophyceae). The biosynthesized ZnO-NPs were characterized UV spectroscopy, Fourier transform infrared X-ray diffraction, transmission electron microscopy, zeta potential analysis. Their antimicrobial activity was assessed the disk diffusion method, revealing significant efficacy against two bacterial species (Klebsiella pneumoniae Escherichia coli) fungal (Candida albicans Aspergillus niger). Additionally, antioxidant of evaluated based on total capacity, ferric reducing power, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assays. confirmed three U. lactuca recorded highest activity. cytotoxicity tested different cell lines MTT assay. showed very weak cytotoxic effects WI 38 (84.98 ± 4.6 µg/mL) 23, this result its safety normal cells. moderate HepG-2 (46.66 2.8 MCF-7 (30.60 2.1 lines. In an in vivo study, a decrease tumor volume, weight, serum malondialdehyde experimental mice, while capacity increased. Histopathological changes indicated reduction size, lower number mitosis divisions, rise apoptosis correlated with lactuca-treated groups. conclusion, seaweed potent antimicrobial, antioxidant, antitumor activities, which can be used pharmaceutical industry.

Язык: Английский

Boron-reinforced zinc oxide nanoparticles produced by the hydrothermal method: A novel antimicrobial agent

MRS Communications, Год журнала: 2024, Номер 14(1), С. 121 - 128

Опубликована: Янв. 8, 2024

Язык: Английский

Biological Activities of Boron and Reduced Graphene Oxide-Based Zinc Oxide Nanocomposites (ZnO:B and RGO/ZnO:B) Synthesized by an Environmentally Friendly Method

Brazilian Journal of Physics, Год журнала: 2023, Номер 54(2)

Опубликована: Дек. 28, 2023

Язык: Английский