PIDA as an Iodinating Reagent: Visible‐Light‐Induced Iodination of Pyrazolo[1,5‐a]pyrimidines and Other Heteroarenes DOI

Suvam Paul,

Sourav Das,

Tathagata Choudhuri

и другие.

Chemistry - An Asian Journal, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 4, 2024

We have developed a visible-light-mediated convenient and efficient strategy for the iodination of heteroarenes using diacetoxyiodobenzene (PIDA) under photocatalyst-free conditions. This unique approach is first report on photocatalytic C-H employing PIDA as iodinating agent. The new applicable to wide range pyrazolo[1,5-a]pyrimidine derivatives with various functionalities. Iodination other electron-rich heterocycles like imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrimidine, imidazo[2,1-b]thiazole, benzo[d]imidazo[2,1-b]thiazole, pyrazoles has been accomplished this benign protocol. usefulness 3-iodo synthetic intermediate in synthesizing functionalized pyrazolo[1,5-a]pyrimidines demonstrated.

Язык: Английский

Recent Progress in Synthetic Applications of Hypervalent Iodine(III) Reagents DOI Creative Commons
Akira Yoshimura, Viktor V. Zhdankin

Chemical Reviews, Год журнала: 2024, Номер unknown

Опубликована: Сен. 13, 2024

Hypervalent iodine(III) compounds have found wide application in modern organic chemistry as environmentally friendly reagents and catalysts. iodine are commonly used synthetically important halogenations, oxidations, aminations, heterocyclizations, various oxidative functionalizations of substrates. Iodonium salts arylating reagents, while iodonium ylides imides excellent carbene nitrene precursors. Various derivatives benziodoxoles, such azidobenziodoxoles, trifluoromethylbenziodoxoles, alkynylbenziodoxoles, alkenylbenziodoxoles group transfer the presence transition metal catalysts, under metal-free conditions, or using photocatalysts photoirradiation conditions. Development hypervalent catalytic systems discovery highly enantioselective reactions chiral represent a particularly recent achievement field chemistry. Chemical transformations promoted by many cases unique cannot be performed any other common, non-iodine-based reagent. This review covers literature published mainly last 7-8 years, between 2016 2024.

Язык: Английский

Процитировано

33

PIDA as an Iodinating Reagent: Visible‐Light‐Induced Iodination of Pyrazolo[1,5‐a]pyrimidines and Other Heteroarenes DOI

Suvam Paul,

Sourav Das,

Tathagata Choudhuri

и другие.

Chemistry - An Asian Journal, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 4, 2024

We have developed a visible-light-mediated convenient and efficient strategy for the iodination of heteroarenes using diacetoxyiodobenzene (PIDA) under photocatalyst-free conditions. This unique approach is first report on photocatalytic C-H employing PIDA as iodinating agent. The new applicable to wide range pyrazolo[1,5-a]pyrimidine derivatives with various functionalities. Iodination other electron-rich heterocycles like imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrimidine, imidazo[2,1-b]thiazole, benzo[d]imidazo[2,1-b]thiazole, pyrazoles has been accomplished this benign protocol. usefulness 3-iodo synthetic intermediate in synthesizing functionalized pyrazolo[1,5-a]pyrimidines demonstrated.

Язык: Английский

Процитировано

1