Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 18, 2024
Abstract
In
this
research,
a
novel
protocol
for
the
synthesis
of
imidazole
derivatives
with
various
substitutions
has
been
investigated
in
presence
new
and
highly
effective
magnetic
decorated
DL-methionine
amino
acid
grafted
onto
chitosan
backbone
by
using
EDTA
linker
(CS
−
MET@Fe3O4)
under
green
chemistry
conditions.
The
CS
MET@Fe3O4
nanocomposite
was
properly
characterized
FTIR,
EDX,
XRD,
FESEM,
TGA
VSM
spectroscopic,
microscopic,
or
analytical
methods.
used
as
efficient
heterogeneous
organocatalyst
wide
range
three-
four-substituted
derivatives,
an
important
pharmaceutical
scaffold,
through
multicomponent
reactioins
(MCRs)
strategy.
multifunctional
nanocatalyst
exhibited
high
catalytic
activity,
selectivity,
stability
to
promote
reactions
benzoin
benzyl,
different
aldehyde
ammonim
acetate
well
aromatic
aliphatic
amine
EtOH
solvent.
Key
advantages
present
are
excellent
yields,
use
low
loading
renewable,
bio-based
biodegredable
chitosan-
acid-based
nanomaterial,
simple
procedure
preparation
nanomaterial
imoidazole
derivatives.
addition,
catalyst's
properties,
including
its
properties
appropriate
surface
area
characteristicscontribute
performance.
Fuerthermore,
can
be
up
six
cycles
only
slight
decrease
activity.
