BioNanoScience, Год журнала: 2024, Номер 15(1)
Опубликована: Дек. 17, 2024
Язык: Английский
Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 99, С. 105983 - 105983
Опубликована: Июль 20, 2024
Процитировано
6
Neuroscience, Год журнала: 2024, Номер 553, С. 1 - 18
Опубликована: Июнь 27, 2024
Язык: Английский
Процитировано
5
Medicine in Novel Technology and Devices, Год журнала: 2024, Номер 24, С. 100327 - 100327
Опубликована: Авг. 27, 2024
Hepatocellular carcinoma (HCC) continues to be a diagnostic and therapeutic challenge for healthcare systems around the world in addition being significant contributor oncologic mortality. To improve standard of life survival patients, early diagnosis condition subsequent appropriate treatment are essential. observation, detection, diagnosis, follow-up all depend heavily on imaging modalities. They provide valuable information about characteristics HCC nodules, aiding non-invasive staging. Imaging has evolved beyond simply confirming suspected management hepatocellular (HCC). Several traditional modalities, including PET/CT, MRI, MR elastography, ultrasound (US), endoscopy, along with next-generation modalities such as photoacoustic imaging, Cerenkov luminescence utilization contrasting agents further enhance their capabilities HCC. The selection most modality agent depends various factors, clinical scenario, patient characteristics, availability resources. In these advancements, artificial intelligence (AI) developed tool radiology this review, we highlighted important techniques managing patients high risk
Язык: Английский
Процитировано
3
Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Ноя. 26, 2024
Angiogenesis is the formation of blood vessels from existing vasculature, which important in tumor growth where metastatic spread, cancer cells depends on an adequate supply oxygen and nutrients removal waste products. Targeting angiogenesis has emerged as a promising therapeutic strategy for treatment. This study presents synthesis evaluation novel Ag-CeO2-ZnO (AgCZ) nanocomposite designed to specifically inhibit effective therapy. The was synthesized via glycine-assisted combustion method, its physicochemical properties were meticulously characterized using advanced analytical techniques. anti-angiogenesis potential AgCZ vigorously explored through assortment vitro investigations, with particular interest inhibiting agents like vascular endothelial factor (VEGF). In silico data molecular docking studies instrumental elucidating nanocomposite's primary reported mechanism action, i.e., strong VEGF target bond. Notably, had selective cytotoxicity different types no sign serious influence onto normal cells, reflecting great promise targeted Not importantly, implemented measure anti-angiogenic well anti-tumor effect biological models additionally. Our highlights emerging developments medicine draws possible future paths. use composite nanoparticle one anticancer drug alternative conventional appears be safer more effectual, but further research needed overcome current limitations clinical translation.
Язык: Английский
Процитировано
3
Current Pharmaceutical Design, Год журнала: 2024, Номер 30(10), С. 727 - 741
Опубликована: Март 1, 2024
Abstract: This review investigates the revolutionary application of cell membrane-coated nanoparticles (CMNPs) as a promising avenue for cancer therapy within embryonic landscape nanotechnology. Nanoparticles, pivotal in treatment, are systematically examined their diverse physicochemical structures, categorized organic (lipid-based, protein-based, and polymer-assisted) inorganic (carbon-based metal) varieties. A significant focus is placed on CMNPs, which serve an innovative drug delivery vehicle, overcoming limitations associated with conventional nanoparticle therapies. manuscript accurately explores advantages challenges various membranes, including those derived from cells, red blood platelets, stem white cells. Importance roles enhancing precision, immune system circumvention, targeted recognition. Detailed insights into crafting CMNPs provided, elucidating membrane extraction fusion techniques, such sonication, extrusion, co-extrusion, microfluidic electroporation. Maintaining integrity during benefits coating techniques augmenting biocompatibility underscored. comprehensive resource consolidates latest advancements delivery, positioning itself at forefront nanotechnology biomedicine research. Encapsulating methodologies like electrospray, chemical conjugation, this showcases expanding toolbox available to researchers dynamic field. Focusing unique characteristics multifaceted applications biomedical research, particularly tumour therapy. It provides indepth analysis stability, evasion capabilities, increased payload capacity, retained biological functionality. The outlines current future prospects chemotherapy, photothermal photodynamic therapy, immunotherapy, gene therapeutic methods. concludes by highlighting transformative potential reshaping treatment.
Язык: Английский
Процитировано
2
Results in Surfaces and Interfaces, Год журнала: 2024, Номер 17, С. 100323 - 100323
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 11 - 25
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
0
BioNanoScience, Год журнала: 2024, Номер 15(1)
Опубликована: Дек. 17, 2024
Язык: Английский
Процитировано
0