A new approach to non-enzymatic glucose sensing with real blood sample analysis: Utilizing nickel-cobalt tungstate
Chemical Engineering Journal,
Год журнала:
2025,
Номер
unknown, С. 158982 - 158982
Опубликована: Янв. 1, 2025
Язык: Английский
Modern screen-printed carbon electrodes modified with multilayered double transition metals carbides (MXenes) for Ascorbic Acid Detection in Urine and sweat samples
Journal of Molecular Structure,
Год журнала:
2025,
Номер
1342, С. 142738 - 142738
Опубликована: Май 27, 2025
Язык: Английский
Recent advances and future perspectives in electrochemical sensing of biomarkers by using MOF- based electrode materials
Mani Arivazhagan,
Samikannu Prabu,
Mari Elancheziyan
и другие.
Emergent Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 28, 2024
Abstract
Metal-organic
frameworks
(MOF)
are
an
extraordinarily
versatile
class
of
porous
nanostructured
materials
that
have
gained
popularity
in
several
scientific
fields.
Organic
ligands
coupled
to
the
inorganic
metal
centers
or
clusters
produce
MOFs.
This
frontier
review
paper
critically
summarizes
most
recent
developments
MOF-based
for
electrochemical
(EC)
detection
key
biomarkers,
including
glucose,
dopamine,
lactic
acid,
L-tryptophan,
uric
and
ascorbic
acids,
H
2
O
,
nicotine.
Various
techniques,
such
as
cyclic
voltammetry
(CV),
chronoamperometry,
differential
pulse
(DPV)
been
employed
enhance
sensitivity
specificity.
EC
sensing
systems
hold
promise
medical
diagnostics,
particularly
diseases
diabetes,
neurodegenerative
cardiovascular
disorders,
cancer.
These
sensors
offer
distinctive
features
like
extensive
specific
surface
area,
tunable
pore
sizes,
exceptional
catalytic
performance,
abundant
active
sites,
enabling
sensitive,
rapid,
cost-effective
biomarker
detection.
The
construction
different
nanostructures,
nanoparticles,
nanorods,
nanowires,
three-dimensional
networks,
has
further
improved
electro-catalytic
efficiency
materials.
We
also
assess
performance
advanced
MOF-derived
sensor
platforms,
discuss
future
challenges
potential
improvements,
enzyme-free
clinical
diagnostics.
work
underscores
effective
tools
detecting
a
wide
range
compounds
biomolecules
relevant
human
health.
Graphical
abstract
Язык: Английский
Point-of-Care Detection of Carcinoembryonic Antigen (CEA) Using a Smartphone-Based, Label-Free Electrochemical Immunosensor with Multilayer CuONPs/CNTs/GO on a Disposable Screen-Printed Electrode
Biosensors,
Год журнала:
2024,
Номер
14(12), С. 600 - 600
Опубликована: Дек. 7, 2024
In
order
to
identify
carcinoembryonic
antigen
(CEA)
in
serum
samples,
an
innovative
smartphone-based,
label-free
electrochemical
immunosensor
was
created
without
the
need
for
additional
labels
or
markers.
This
technology
presents
a
viable
method
on-site
cancer
diagnostics.
The
novel
smartphone-integrated,
immunosensing
platform
constructed
by
nanostructured
materials
that
utilize
layer-by-layer
(LBL)
assembly
technique,
allowing
meticulous
control
over
interface.
Detection
relies
on
direct
interactions
extra
tagging
agents,
where
ordered
graphene
oxide
(GO),
carbon
nanotubes
(CNTs),
and
copper
nanoparticles
(CuONPs)
were
sequentially
deposited
onto
screen-printed
electrode
(SPCE),
designated
as
CuONPs/CNTs/GO/SPCE.
significantly
amplifies
signal,
detection
of
low
concentrations
target
molecules
CEA.
LBL
approach
enables
precise
construction
multi-layered
structures
sensor
surface,
enhancing
their
activity
optimizing
performance
CEA
detection.
These
serve
efficient
carriers
increase
surface
area,
conductivity,
structural
support
antibody
loading,
thus
improving
sensitivity
this
transducer
is
based
decrease
current
response
[Fe(CN)
Язык: Английский
Highly Porous 3D Ni-MOFs as an Efficient and Enzyme-Mimic Electrochemical Sensing Platform for Glucose in Real Samples of Sweat and Saliva in Biomedical Applications
ACS Omega,
Год журнала:
2024,
Номер
10(1), С. 1610 - 1623
Опубликована: Дек. 27, 2024
Nickel-based
metal–organic
frameworks,
denoted
as
three-dimensional
nickel
trimesic
acid
frameworks
(3D
Ni-TMAF),
are
gaining
significant
attention
for
their
application
in
nonenzymatic
glucose
sensing
due
to
unique
properties.
Ni-MOFs
possess
a
high
surface
area,
tunable
pore
structures,
and
excellent
electrochemical
activity,
which
makes
them
ideal
facilitating
electron
transfer
enhancing
the
catalytic
oxidation
of
glucose.
This
research
describes
new
enzyme-mimic
biosensor
biological
solutions
that
utilizes
3D
nanospheres
Ni-TMAF
created
layer-by-layer
on
highly
porous
substrate.
The
based
represent
promising
approach,
leveraging
properties
provide
efficient,
stable,
potentially
more
cost-effective
alternatives
traditional
sensors.
MOF
is
synthesized
from
(TMA)
nitrate
hexahydrate
through
solvothermal
reaction
process.
resulting
crystalline
structure
with
large
area
numerous
active
sites
toward
indeed
known
electrocatalytic
particularly
context
under
alkaline
conditions.
centers
facilitate
efficient
redox
reactions,
leading
sensitivity
203.89
μA
μM–1
cm–2
lower
LOD
0.33
μM
fast
response
time
<3
s
Their
stability,
cost-effectiveness,
performance
make
material
Язык: Английский