Recent advances in delivery systems of ginsenosides for oral diseases
Phytomedicine,
Год журнала:
2025,
Номер
unknown, С. 156422 - 156422
Опубликована: Янв. 1, 2025
Язык: Английский
Ginsenosides in cancer: Proliferation, metastasis, and drug resistance
Biomedicine & Pharmacotherapy,
Год журнала:
2024,
Номер
177, С. 117049 - 117049
Опубликована: Июнь 29, 2024
Ginseng,
the
dried
root
of
Panax
ginseng
C.A.
Mey.,
is
widely
used
in
Chinese
herbal
medicine.
Ginsenosides,
primary
active
components
ginseng,
exhibit
diverse
anticancer
functions
through
various
mechanisms,
such
as
inhibiting
tumor
cell
proliferation,
promoting
apoptosis,
and
suppressing
invasion
migration.
In
this
article,
mechanism
action
20
ginsenoside
subtypes
therapy
research
progress
multifunctional
nanosystems
are
reviewed,
order
to
provide
reference
for
clinical
prevention
treatment
cancer.
Язык: Английский
Nanovaccine of tumor-derived antigenic microparticles for enhancing effect of arsenic trioxide in cancer immunotherapy
Nano Today,
Год журнала:
2024,
Номер
57, С. 102321 - 102321
Опубликована: Май 23, 2024
Язык: Английский
Hybrid cell membranes camouflage liposomes containing payloads to improve breast cancer chemo and photodynamic therapy
Biomaterials Science,
Год журнала:
2024,
Номер
12(19), С. 4980 - 4992
Опубликована: Янв. 1, 2024
Developing
a
novel
biomimetic
material,
Dox-IR780@Lip@Ms,
aims
to
optimize
drug
delivery,
reduce
the
side
effects
of
drugs,
and
synergistically
enhance
therapeutic
effect
for
unresectable
locally
advanced
breast
cancer
and/or
metastasis.
Язык: Английский
Formulation of Lipid Nanoparticles Containing Ginsenoside Rg2 and Protopanaxadiol for the Highly Efficient Delivery of mRNA
Biomaterials Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
We
developed
novel
LNPs
as
an
mRNA
delivery
system
by
replacing
cholesterol
with
ginsenoside
Rg2
and
its
derivative
phytosterol
protopanaxadiol
(PPD).
Both
Rg2-LNP
PPD-LNP
demonstrated
highly
efficient
expression.
Язык: Английский
Temperature-Dependent Cytokine Neutralization Induced by Magnetoelectric Nanoparticles: An In Silico Study
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(24), С. 13591 - 13591
Опубликована: Дек. 19, 2024
Inflammatory
cytokines
cooperate
to
maintain
normal
immune
homeostasis,
performing
both
a
protective
and
pro-inflammatory
action
in
different
body
districts.
However,
their
excessive
persistence
or
deregulated
expression
may
degenerate
into
tissue
chronic
inflammatory
status.
Advanced
therapies
should
be
designed
deploy
selective
cytokine
neutralizers
the
affected
tissues.
Magnetoelectric
nanoparticles
(MENPs)
possess
unexploited
potentialities,
conjugating
ferromagnetic
nature,
which
enables
confinement
specific
by
directed
positioning
when
subjected
low-intensity
magnetic
fields,
with
capability
generate
high
electric
fields
elevated
spatial
resolution
higher
fields.
This
work
proposes
exploit
extremely
localized
heat
generated
Joule’s
effect
around
MENPs
under
an
external
field
denature
harmful
hypothetical
site.
An
interdisciplinary
multiphysics
silico
study
was
conducted
provide
comprehensive
modeling
of
temperature
distribution
decorated
membrane-derived
microvesicle
(MV)
coating
allocate
antibody
bind
target
cytokine.
A
damage
model
also
implemented
estimation
influence
several
design
parameters
on
denaturation
efficacy,
final
goal
guiding
future
development
effective
MENPs-based
therapeutic
applications
strategies.
Язык: Английский