Development of a fluorescent probe for detecting superoxide anions for monitoring the progression and treatment of acute spondylitis DOI

Xiaoming Chen,

Peng Li, Guiqing Wang

и другие.

Analytical Methods, Год журнала: 2024, Номер 17(3), С. 533 - 538

Опубликована: Дек. 10, 2024

The superoxide anion (O2˙-) is a vital reactive oxygen species (ROS) and participates in various physiological pathological processes organisms. outbreak of O2˙- the endoplasmic reticulum (ER) believed to be closely related many inflammatory diseases. In this work, turn-on type ER-targeting fluorescent probe ERO was rationally designed for sensitive selective detection O2˙-. minimum limit concentration about 3.3 × 10-7 M aqueous solution. More importantly, has minimal biological toxicity can effectively target ER detect macrophage cells. Resveratrol natural drug anti-inflammatory effects. Through fluorescence monitoring ERO, it found that there an acute spondylitis mice resveratrol reversed increase. Thus, potential become favorable diagnostic tool visualize mouse spine during inflammation therapeutic effect resveratrol.

Язык: Английский

Light-controllable enzymatic emission shift for spatiotemporal ratiometric imaging of tyrosinase activity in living cells and zebrafish DOI

Z. Zhang,

Zhenzhen Fan,

Jinglong Jiao

и другие.

Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137538 - 137538

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Recent progress towards the development of fluorescent probes for the detection of disease-related enzymes DOI
Lopamudra Mishra, Monalisa Mishra

Journal of Materials Chemistry B, Год журнала: 2024, Номер unknown

Опубликована: Дек. 6, 2024

This review highlights the current advancements in development of fluorescent probes for selective detection disease-relevant enzymes, focusing on their biocompatibility vivo models.

Язык: Английский

Процитировано

1
Development of a fluorescent probe for detecting superoxide anions for monitoring the progression and treatment of acute spondylitis DOI

Xiaoming Chen,

Peng Li, Guiqing Wang

и другие.

Analytical Methods, Год журнала: 2024, Номер 17(3), С. 533 - 538

Опубликована: Дек. 10, 2024

The superoxide anion (O2˙-) is a vital reactive oxygen species (ROS) and participates in various physiological pathological processes organisms. outbreak of O2˙- the endoplasmic reticulum (ER) believed to be closely related many inflammatory diseases. In this work, turn-on type ER-targeting fluorescent probe ERO was rationally designed for sensitive selective detection O2˙-. minimum limit concentration about 3.3 × 10-7 M aqueous solution. More importantly, has minimal biological toxicity can effectively target ER detect macrophage cells. Resveratrol natural drug anti-inflammatory effects. Through fluorescence monitoring ERO, it found that there an acute spondylitis mice resveratrol reversed increase. Thus, potential become favorable diagnostic tool visualize mouse spine during inflammation therapeutic effect resveratrol.

Язык: Английский

Процитировано

0