Construction of C–S and C–Se Bonds via Photocatalytic Aromatization-Driven Deconstructive Diversification of Spiro-Dihydroquinazolinones Derived from Unstrained Ketones
Tao Wang,
Jin‐Long Dai,
Yifeng Jiang
и другие.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 13, 2025
A
novel
and
robust
deconstructive
functionalization
reaction
of
spiro-dihydroquinazolinones
with
sulfenylating
reagents
in
the
presence
base
has
been
realized
under
visible
light
irradiation.
This
enabled
direct
ring-opening
unstrained
cyclic
ring
systems,
producing
skeletally
diverse
functionalized
quinazolinones
moderate
to
good
yields.
range
variety
including
diaryl
disulfide,
thiosulfonate,
dithiosulfonate
1-[(trifluoromethyl)thio]-2,5-pyrrolidinedione
were
compatible
for
this
transformation.
In
addition,
diselenide
selenosulfonate
could
also
couple
form
C-Se
Bonds.
Mechanistic
studies
revealed
that
proceeds
via
a
radical-radical
coupling
pathway.
Язык: Английский
(Vinyl triflimide)benziodolium Salts: Palladium-Catalyzed Cascade Reactions toward Unsymmetrical Benzils
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 28, 2025
(Vinyl
triflimide)benziodolium
salts
were
developed
as
new
hypervalent
iodine
reagents.
A
cascade
of
diarylation/oxidation
reactions
with
the
benziodolium
was
accomplished
in
presence
palladium
catalysts.
The
reaction
exhibits
extensive
compatibility
readily
available
arylboronic
acids,
giving
a
diverse
array
benzyl
derivatives
good
yields.
benzils
can
serve
versatile
intermediates
fine
chemical
synthesis.
Язык: Английский