Shining a Light on Peptide and Protein Synthesis: Light-Emitting-Diode-Driven Desulfurization of Cysteine to Alanine with Rose Bengal

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Янв. 23, 2025

Studies presenting visible-light-induced desulfurization of peptides containing a cysteine residue have been carried out. This transformation driven by light-emitting-diode-type light proceeds with high efficiency in an aqueous solution at room temperature and involves the use catalytic amount photosensitizer, Rose Bengal. The procedure has tested on model synthetic peptides, lysozyme C α-crystallin, successfully applied to one-pot native chemical ligation (NCL)–desulfurization protocol.

Язык: Английский

Facile Construction of Supported Polyoxometalate Ionic Liquids for Deep Oxidative Desulfurization of Fuel

Catalysts, Год журнала: 2024, Номер 14(11), С. 796 - 796

Опубликована: Ноя. 7, 2024

A series of commercial silica-supported polyoxometalate ionic liquids ([Cnmim]3PMo12O40) with different substitutes in the imidazole ring were prepared via a facile ball milling method and employed as catalysts oxidative desulfurization organosulfur compounds. The experimental results demonstrated that active center was successfully immobilized highly uniform dispersion on silica. Without any organic solvent extractant, sulfur removal sample C16PMo/SiO2-BM reached 99.5% 30 min under optimal condition, which ascribed to high specific surface area lipophilicity. In addition, site verified by free radical trapping experiment an ESR spin capture experiment. product confirmed GC-MS analysis.

Язык: Английский