International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(22), С. 11861 - 11861
Опубликована: Ноя. 5, 2024
Molecular cages are preorganized molecules with a central cavity, typically formed through the reaction of their building blocks chemical bonds. This requires, in most cases, forming and breaking reversible bonds during cage formation pathway for error correction to drive product. In this work, we focus on both Pd-ligand hydrazone implemented structure Pd
Язык: Английский
Journal of the American Chemical Society, Год журнала: 2025, Номер unknown
Опубликована: Март 2, 2025
The development of new chiral building blocks for constructing complex architectures, such as macrocycles and cages, is both crucial challenging. Although concave-shaped calixarenes have been established versatile the synthesis cage compounds, there are no reports on cages constructed from calix[4]arene derivatives. Herein, we present a straightforward effective method gram-scale member macrocycle enantiomers, namely, phenol[4]arene (PC[4]A). As proof concept, functionalized these enantiomers into tetraformylphenol[4]arene (PC[4]ACHO) derivatives via Duff reaction to construct porous organic (CPOCs) using polyamine synthons. Specifically, employ two fluorescent amine synthons, bis(4-aminophenyl)phenylamine tris(4-aminophenyl)amine, assemble with PC[4]ACHO resulting in [2 + 4] lantern-shaped [6 8] truncated octahedral CPOCs, respectively. These structures unambiguously characterized by single-crystal X-ray diffraction circular dichroism (CD) spectroscopy. Notably, CPOCs exhibit internal diameters approximately 3.1 nm, cavity volume around 5300 Å3, high specific surface areas up 1300 m2 g-1 after desolvation, making them among largest reported. Additionally, investigations their sensing performance demonstrate that PC[4]A-based enable enantioselective recognition amino acids This work strongly suggests PC[4]A can serve an excellent block rational design materials practical applications.
Язык: Английский
Процитировано
1
Crystal Growth & Design, Год журнала: 2025, Номер unknown
Опубликована: Янв. 15, 2025
A biological self-assembly of organized supramolecular structures and functional materials has emerged as a significant research focus in recent decades. Different strategies have been proposed successfully adopted for engineering complex structures. Among others, substantial progress made using dynamic covalent chemistry (DCC) to generate with sophisticated properties. This Perspective elaborates on the role carbon–carbon (C–C)-based diradical-based DCC self-assembly. It provides an in-depth discussion structural aspects C–C bonds discrete oligomer formation including dimers, trimers, tetramers, hexameric Early sections survey critical factors contributing longevity stability radical systems influences substitution diradicals into dimers or macrocycles. Significant attention given characteristics diradical impact hydrogen π–π interactions configurations self-assembled The latter part this article properties applications DCC-mediated primary objectives review are (i) present detailed analysis benefits associated diradical-mediated (ii) investigate their
Язык: Английский
Процитировано
0
Inorganic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Фев. 6, 2025
Flexible metal–organic cages can provide confined active metal sites and show promise in mimicking metalloenzymes. In this study, we synthesized two flexible chiral bimetallic coordination cages, [(PEt3)6Pt3(R,R,R-VL)2]6+ its enantiomer, through the self-assembly of platinum(II) precursors with enantiopure tripodal vanadium(V) complexes bearing pendant pyridyl groups (VL). The guest binding camphorsulfonate anions, concomitant changes cage conformation. catalytic properties for oxidizing thioethers into sulfoxides were investigated comparison a simple complex. While complex, either alone or along camphorsulfonate, does not any enantioselectivity, enables enantioselective oxidation even though enantiomeric excess is low. stereoselectivity significantly improved after introduced to cage. acts like an allosteric effector enzymes modulate conformation local microenvironment around site favor induction. This work highlights potentials leveraging cage-confined host–guest interactions advancing supramolecular asymmetric catalysis.
Язык: Английский
Процитировано
0
Beilstein Journal of Organic Chemistry, Год журнала: 2025, Номер 21, С. 421 - 443
Опубликована: Фев. 24, 2025
The bespoke environments in enzyme active sites can selectively accelerate chemical reactions by as much 1019. Macromolecular and supramolecular chemists have been inspired to understand mimic these accelerations selectivities for applications catalysis sustainable synthesis. Over the past 60+ years, mimicry strategies evolved with changing interests, understanding, synthetic advances but, ubiquitously, research has focused on use of a molecular "cavity". activities different cavities vary subset features available particular cavity type. Unsurprisingly, without access mimics able encompass more/all functional sites, examples cavity-catalyzed processes demonstrating enzyme-like rate remain rare. This perspective will briefly highlight some key traditional catalysis, type, order contextualize recent development robust organic cage catalysts, which exploit stability, functionality, reduced symmetry enable promising catalytic modes.
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161326 - 161326
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(22), С. 11861 - 11861
Опубликована: Ноя. 5, 2024
Molecular cages are preorganized molecules with a central cavity, typically formed through the reaction of their building blocks chemical bonds. This requires, in most cases, forming and breaking reversible bonds during cage formation pathway for error correction to drive product. In this work, we focus on both Pd-ligand hydrazone implemented structure Pd
Язык: Английский
Процитировано
0