Probiotic Limosilactobacillus reuteri DSM 17938 Alleviates Acute Liver Injury by Activating the AMPK Signaling via Gut Microbiota–Derived Propionate

Probiotics and Antimicrobial Proteins, Год журнала: 2025, Номер unknown

Опубликована: Янв. 28, 2025

Язык: Английский

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Immunomodulatory effects of Lactiplantibacillus plantarum CCFM8661 + stachyose on cyclophosphamide-induced immunosuppression mice

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Янв. 27, 2025

Introduction The increasing stress of modern life has led to a decline in immunity, sparking widespread interest new strategies boost immune function. Lactiplantibacillus plantarum and stachyose have gained attention for their immune-regulating effects, but the mechanisms combined application remain unclear. This study aims investigate immunoregulatory effects CCFM8661 with cyclophosphamide-induced immunocompromised mice. Methods Mice were divided into normal control group, model group (normal saline), positive drug (levamisole hydrochloride, 10 mg/kg), low, medium, high-dose groups (1.5×10 5 , 1.5×10 6 7 CFU + 1.5 mg stachyose). Each treatment received continuous oral gavage administration 28 days. On days 23 24, except all other intraperitoneally injected cyclophosphamide (40 mg/kg) establish an immunosuppressed model. day 28, 30 minutes after final administration, mice euthanized collect thymus, spleen, serum, ileum, feces subsequent analysis indicators, intestinal barrier function, serum cytokines, microbiota. Results combination significantly improved organ atrophy, restored morphology, normalized cytokine levels mice, indicating enhanced Additionally, it microbiota diversity by abundance Muribaculaceae while reducing Lachnospiraceae potentially promoting homeostasis. Discussion immune-enhancing achieved regulating inflammation maintaining

Язык: Английский

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Role of peroxisomes in the pathogenesis and therapy of renal fibrosis

Metabolism, Год журнала: 2025, Номер 166, С. 156173 - 156173

Опубликована: Фев. 22, 2025

Язык: Английский

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Effect of lead exposure on silkworm midgut: Insights into oxidative gene expression, digestive function, and microbial community structure

Process Safety and Environmental Protection, Год журнала: 2024, Номер 190, С. 481 - 494

Опубликована: Июль 16, 2024

Язык: Английский

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Covalent organic framework-based materials for ion separation: A review

Chemical Engineering Journal, Год журнала: 2024, Номер 504, С. 158745 - 158745

Опубликована: Дек. 18, 2024

Язык: Английский

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Effects of biochar-supported nano-hydroxyapatite on cadmium availability and pepper growth in contaminated soils

The Science of The Total Environment, Год журнала: 2024, Номер 956, С. 177303 - 177303

Опубликована: Ноя. 5, 2024

Язык: Английский

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