Pharmaceuticals,
Год журнала:
2024,
Номер
17(12), С. 1738 - 1738
Опубликована: Дек. 23, 2024
Given
the
current
global
circumstances,
marked
by
severe
environmental
pollution—including
contamination
of
food—along
with
daily
stress
and
a
sedentary
lifestyle,
many
consumers
choose
to
improve
their
quality
life
using,
among
others,
minimally
processed
food,
food
supplements,
gemmo-derivatives.
Recent
lab
clinical
studies
have
shown
positive
impact
specific
nutrients
antioxidant
capacities
in
treatment
several
conditions
generated
oxidative
stress.
This
paper
reviews
plant
extracts
utilized
as
components
various
dietary
supplements
gemmoderivatives,
highlighting
chemical
composition
biological
properties
preventing
diseases
caused
A
modern
approach
science
brings
fore
concept
vs.
functional
nutraceuticals,
The
definitions
these
terms
are
not
being
unanimously
regulated
this
respect
describe
each
category
compound
product,
also
emphasizing
need
implement
adequate
nutrivigilance.
In
order
enhance
absorption
bioavailability
gemmo-derivatives
based
on
extracts,
some
encapsulation
techniques
outlined.
Molecules,
Год журнала:
2025,
Номер
30(1), С. 189 - 189
Опубликована: Янв. 6, 2025
Propolis
is
a
valuable
natural
resource
for
extracting
various
beneficial
compounds.
This
study
explores
sustainable
extraction
approach
Brazilian
green
propolis.
First,
supercritical
fluid
(SFE)
process
parameters
were
optimized
(co-solvent:
21.11%
v/v
CPME,
and
temperature:
60
°C)
to
maximize
yield,
total
phenolic
content
(TPC),
antioxidant
capacity,
LOX
(lipoxygenase)
inhibitory
activity.
GC–MS
analysis
identified
40
metabolites
in
SFE
extracts,
including
fatty
acids,
terpenoids,
phenolics,
sterols.
After
selecting
the
optimum
parameters,
sequential
high-pressure
(HPE)
was
developed,
comprising
SFE,
pressurized
liquid
(PLE)
with
EtOH/H2O,
subcritical
water
(SWE).
compared
similar
using
low-pressure
extractions
(LPE)
Soxhlet
extractor.
The
HPE
achieved
significantly
higher
overall
yield
(80.86%)
than
LPE
(71.43%).
showed
selectivity,
resulting
lower
carbohydrate
non-polar
fraction,
PLE
extracted
nearly
twice
protein
amount
of
LPE–2.
Despite
extracts
exhibited
better
acetylcholinesterase
(AChE),
butyrylcholinesterase
(BChE),
inhibition,
demonstrating
that
neuroprotective
anti-inflammatory
activity
may
be
associated
symbiosis
set
Finally,
comprehensive
greenness
assessment
revealed
proved
more
aligned
chemistry
principles
method.
Food Science & Nutrition,
Год журнала:
2025,
Номер
13(3)
Опубликована: Март 1, 2025
ABSTRACT
Phenolic
antioxidants
and
curcuminoids
are
biologically
important
molecules
playing
a
crucial
role
in
combating
reactive
species
under
oxidative
stress
conditions.
In
this
study,
microwave‐assisted
extraction
(MAE)
ultrasound‐assisted
(UAE)
processes
for
the
of
phenolic
curcumin
from
turmeric
using
an
ethanol‐water
mixture
were
optimized
modeled
with
face‐centered
composite
design
response
surface
methodology.
Under
optimal
conditions,
CUPRAC
total
antioxidant
capacity
(TAC),
content
(CC),
DPPH
free
radical
scavenging
capacity,
ABTS
contents
(TPC)
extracts
obtained
MAE,
UAE,
automated
soxhlet‐assisted
determined
to
distinguish
water
ratio
ethanolic
solvent
as
most
operational
factor
affecting
TAC
CC
responses.
The
highest
yields
at
200
μm
particle
size,
100°C
temperature,
30
min
time,
20%
ethanol
conditions
MAE.
48
G
=
600
W
ultrasonic
power,
26%
UAE.
addition,
red
lentil
(R.L.)
soup
was
selected
model
food
system
enriched
by
UAE
process.
effects
addition
protein‐rich
matrix,
spontaneous
protein‐curcumin
interaction,
existence
olive
oil
oil/water
emulsion
delivery
prepared
samples
investigated
association
simulated
gastrointestinal
digestion.
(R.L
+
5%
extract)
sample
shown
have
higher
TPC
value
than
analogous
mixtures
after
vitro
values
those
without
due
potential
ability
provide
solubility
stability
together
its
source.
solubility,
oil–water
interfacial
absorption,
measured
before
Curcumin
foods
may
be
recommended
considering
health‐promoting
functional
foods.
proposed
show
recover
bioactive
compounds
high
efficiency
through
green
chemistry
new
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Март 22, 2025
Liquorice
(Glycyrrhiza
glabra
L.)
root
extract
has
been
used
as
a
natural
medicine
and
sweetener
for
long
time
in
many
parts
of
the
world.
As
result,
there
considerable
emphasis
on
developing
efficient
environmentally
friendly
methods
extracting
bioactive
components
from
root.
This
work
aims
to
examine
using
combined
ultrasonic-cold
plasma
reactor
elevate
extraction
efficiency.
Different
parameters,
including
time,
ultrasonic
power,
argon-to-air
ratio,
were
investigated
Response
Surface
Methodology
(RSM)
Box-Behnken
design
raise
quality.
The
total
phenol
flavonoid
content
antioxidant
activity
calculated
evaluate
this
approach,
Glycyrrhizic
acid
was
quantified
by
HPLC
(High-performance
liquid
chromatography).
Results
showed
that
combining
greatly
raised
yield
compared
conventional
maceration
single-method
methods.
Particularly,
10.23,
15.96,
13.29%,
21.47,
22.19,
42.41%,
10.84%,
12.38%,
15.89%
increased
ultrasonic,
cold
plasma,
technique,
respectively,
technique.
Optimization
different
techniques
best
quality
came
mix
composition,
time.
study
demonstrates
technique
is
effective
efficient,
technology
potential
new
method
present
more
sustainable
substitute
premium
extracts
medicinal
commercial
uses.
ACS Sustainable Chemistry & Engineering,
Год журнала:
2024,
Номер
12(43), С. 16052 - 16063
Опубликована: Окт. 17, 2024
The
design
of
new
hydrophobic
solvents
is
essential
for
replacing
the
toxic
hexane
extracting
nonpolar
compounds
such
as
fatty
acids.
On
other
hand,
full
use
plant
matrices
seeking
to
obtain
food
and
pharmaceutical
products
from
their
coproducts
has
also
been
focus
sustainable
processes.
This
study
proposed
extract
acids
bioactive
obtained
almond-
peanut-based
milk
processing.
COSMO-RS
method
was
used
select
terpene-based
mixtures
substitute
hexane.
Experimentally,
four
liquid
were
formed
1:2
tetradecanol/1,8-cineole
(TE/EU),
camphor/1,8-cineole
(CA/EU),
1:1
oleic
acid/1,8-cineole
(OL/EU),
menthol/1,8-cineole
(ME/EU).
DSC
analyses
indicated
reduction
CA/EU,
OL/EU,
ME/EU
melting
points
concerning
components.
However,
point
values
predicted
by
COSMO
obtaining
eutectic
differed.
CA/EU
only
mixture
with
a
lower
than
COSMO-RS-predicted
one.
In
contrast,
FTIR
spectra
did
not
provide
clear
visualization
hydrogen
bond
formation
between
camphor
1,8-cineole.
could
be
due
weak
bonds,
phenomenon
observed
in
studies.
Nevertheless,
these
have
advantage
low
viscosity,
promising
feature
that
likely
facilitated
mass
transfer
extraction
almond
peanut
coproducts.
provided
same
global
yield
higher
phytosterol
squalene
content
extracts
can
directly
applications
since
are
usually
part
formulations.
TGA-DTA
possible
ways
separate
solvents.
