Visible-Light-Induced Synergistic W/Cr Catalyzed gem-Difluoroallylation of Unactivated Alkanes
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 19, 2025
Currently,
the
scope
of
Nozaki-Hiyama-Kishi
(NHK)
reaction
is
limited
to
aldehydes
and
ketones
construct
alcohol
derivatives.
Herein,
we
have
described
a
visible-light-induced
synergistic
W/Cr(III)-catalyzed
NHK-type
gem-difluoroallylation
unactivated
cyclic
linear
alkanes.
The
merits
feedstock
materials,
mild
conditions,
wide
functionality
tolerance.
Mechanistic
studies
imply
favorable
reduction
CrCl3
CrCl2
by
reduced
decatungstate
W10O325-,
thus
closing
catalytic
cycle.
Язык: Английский
Late-Stage Heteroarene Alkylation via Minisci Reaction with Gaseous Alkanes Enabled by Hydrogen Atom Transfer in Flow
ACS Central Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 12, 2025
Язык: Английский
Reactivity Tuning for Selective Aldimino-Sulfonylation of Styrenes by Photocatalytic Activation of Sulfonyl Aldimines
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 31, 2025
Imino-sulfonylation
of
styrene
represents
a
powerful
method
for
constructing
highly
functionalized
molecules,
while
only
diphenyl
imines
were
able
to
be
employed
in
previous
reports.
By
modulating
the
electron
property
styrene,
visible-light-mediated
radical/radical
cross-coupling
aldiminyl
radical
and
carbon-centered
was
achieved
synthesize
diverse
aldimine-embedded
sulfones
by
using
sulfonyl
aldimines
α-trifluoromethylstyrenes.
One-pot
oxidation
delivered
Ritter-type
amidation
products
without
need
excessive
nitriles
as
solvent.
Furthermore,
this
protocol
took
advantage
simple
reaction
conditions,
good
substituent
diversity,
high
atom
economy
broaden
research
radicals
amination
alkenes.
Язык: Английский