Particle manipulation under X-force fields
Lab on a Chip,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
highlights
recent
technological
advances
for
progress
in
particle
manipulation
under
X-force
fields,
and
forecasts
the
trajectory
of
future
developments.
Язык: Английский
Progressive Approaches in Oncological Diagnosis and Surveillance: Real‐Time Impedance‐Based Techniques and Advanced Algorithms
Bioelectromagnetics,
Год журнала:
2025,
Номер
46(1)
Опубликована: Янв. 1, 2025
ABSTRACT
Cancer
remains
a
formidable
global
health
challenge,
necessitating
the
development
of
innovative
diagnostic
techniques
capable
early
detection
and
differentiation
tumor/cancerous
cells
from
their
healthy
counterparts.
This
review
focuses
on
confluence
advanced
computational
algorithms
with
noninvasive,
label‐free
impedance‐based
biophysical
methodologies—techniques
that
assess
biological
processes
directly
without
need
for
external
markers
or
dyes.
elucidates
diverse
array
state‐of‐the‐art
technologies,
illuminating
distinct
electrical
signatures
inherent
to
cancer
vs
tissues.
Additionally,
study
probes
transformative
potential
these
modalities
in
recalibrating
personalized
treatment
paradigms.
These
offer
real‐time
insights
into
tumor
dynamics,
paving
way
precision‐guided
therapeutic
interventions.
By
emphasizing
quest
continuous
vivo
monitoring,
herald
pivotal
advancement
overarching
endeavor
combat
globally.
Язык: Английский
Tutorial on impedance and dielectric spectroscopy for single-cell characterisation on microfluidic platforms: theory, practice, and recent advances
Lab on a Chip,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Integration
of
low-frequency
electrical
impedance
and
broadband
electromagnetic
sensing
with
microfluidic
devices
enables
high-throughput
analysis
cell
size,
membrane
properties,
intracellular
characteristics.
Язык: Английский
Microfluidic impedance flow cytometer leveraging virtual constriction microchannel and its application in leukocyte differential
Microsystems & Nanoengineering,
Год журнала:
2024,
Номер
10(1)
Опубликована: Дек. 16, 2024
Abstract
Microfluidic
impedance
flow
cytometry
has
been
widely
used
in
leukocyte
differential
and
counting,
but
it
faces
a
bottleneck
due
to
the
trade-off
between
detection
throughput
sensitivity.
In
this
study,
microfluidic
cytometer
based
on
virtual
constriction
microchannel
was
reported,
which
constructed
by
crossflow
of
conductive
sample
insulated
sheath
fluids
with
underneath
micro-electrodes
for
measurements.
Compared
conventional
mechanical
microchannels,
counterpart
could
effectively
avoid
direct
physical
contact
cells
walls
maintain
high
throughputs,
significantly
reduce
volume
region
sensitivity
improvements.
Using
developed
cytometer,
pulses
three
leukemia
cell
lines,
K562,
Jurkat,
HL-60,
were
detected,
achieving
99.8%
differentiation
accuracy
through
use
recurrent
neural
network.
Furthermore,
four
white
blood
subpopulations
(neutrophils,
eosinophils,
monocytes,
lymphocytes)
from
donors
classification
≥99.2%.
A
network
model
established
purified
applied
two
mixtures,
resulting
proportional
distributions
within
theoretical
ranges.
These
results
indicated
that
achieve
both
sensitivity,
showing
great
potentials
clinical
diagnostics
analysis.
Язык: Английский