Hydrogel-Based Inks for Extrusion 3D Printing: A Rheological Viewpoint
Current Opinion in Colloid & Interface Science,
Год журнала:
2025,
Номер
unknown, С. 101918 - 101918
Опубликована: Март 1, 2025
Язык: Английский
Fabrication and Comparative Evaluation of Psyllium Husk Polysaccharide‐Based Lyophilized, Electrospun and Three‐Dimensional Printed Scaffolds for Functional Performance of Primary Hepatocytes
Journal of Applied Polymer Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 25, 2025
ABSTRACT
Psyllium
husk
is
known
for
its
therapeutic
value
and
abundantly
used
in
food,
medicinal,
nutraceutical
applications.
In
the
present
study,
we
have
explored
potential
of
psyllium
polysaccharide
hydrogel
either
alone
or
combination
with
gelatin
culture
maintenance
adult
rat
hepatocytes.
We
designed
fabricated
electrospun
nanofibrous
sheets,
three‐dimensional
(3D)
printed,
lyophilized
scaffolds
using
polysaccharide.
Primary
hepatocytes
were
harvested
from
liver
by
double
perfusion
method
collagenase.
Results
showed
that
all
exhibited
porous
space
a
similar
size
range
100
to
250
μm,
3D
printed
within
200–240
μm
60–190
respectively,
which
reported
support
performance
Furthermore,
morphology
viability
characterization
MTT
assay
revealed
displayed
remarkable
primary
(~280%)
significant
level
aggregate
formation
compared
those
on
collagen‐coated
2D
substrates.
All
supported
hepatocyte
secretion
albumin
(0.1–0.6
mg/mL)
urea
(20
180
μg/mL)
into
extracellular
fluid.
Although
enhanced
spheroid
formation,
viability,
metabolic
functions,
(75‐3DP)
(50‐ES
75‐ES)
functional
performances
(albumin:
0.2–0.6
mg/mL;
urea:
40–180
comparatively.
Язык: Английский
Neem gum and its derivatives as potential polymeric scaffold for diverse applications: a review
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 143012 - 143012
Опубликована: Апрель 1, 2025
Язык: Английский
Tissue Engineering and Regenerative Medicine: Perspectives and Challenges
MedComm,
Год журнала:
2025,
Номер
6(5)
Опубликована: Апрель 24, 2025
ABSTRACT
From
the
pioneering
days
of
cell
therapy
to
achievement
bioprinting
organs,
tissue
engineering,
and
regenerative
medicine
have
seen
tremendous
technological
advancements,
offering
solutions
for
restoring
damaged
tissues
organs.
However,
only
a
few
products
technologies
received
United
States
Food
Drug
Administration
approval.
This
review
highlights
significant
progress
in
therapy,
extracellular
vesicle‐based
engineering.
Hematopoietic
stem
transplantation
is
powerful
tool
treating
many
diseases,
especially
hematological
malignancies.
Mesenchymal
cells
been
extensively
studied.
The
discovery
induced
pluripotent
has
revolutionized
disease
modeling
applications,
paving
way
personalized
medicine.
Gene
represents
an
innovative
approach
treatment
genetic
disorders.
Additionally,
therapies
emerged
as
rising
stars,
promising
diagnostics,
cell‐free
therapeutics,
drug
delivery,
targeted
therapy.
Advances
engineering
enable
complex
constructs,
further
transforming
field.
Despite
these
technical,
ethical,
regulatory
challenges
remain.
addresses
current
bottlenecks,
emphasizing
novel
interdisciplinary
research
overcome
hurdles.
Standardizing
practices
conducting
clinical
trials
will
balance
innovation
regulation,
improving
patient
outcomes
quality
life.
Язык: Английский