Journal of Controlled Release, Год журнала: 2024, Номер 377, С. 716 - 734
Опубликована: Дек. 3, 2024
Язык: Английский
Dalton Transactions, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
We report the anticancer activity of a red light-activable hetero-bimetallic [Fe(iii)–Ru(ii)] complex as next-generation dual-modality PDT tool for photo-activated therapy.
Язык: Английский
Процитировано
1
Materials Today Bio, Год журнала: 2024, Номер 30, С. 101383 - 101383
Опубликована: Дек. 6, 2024
Язык: Английский
Процитировано
5
Acta Biomaterialia, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140820 - 140820
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160659 - 160659
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Beilstein Journal of Nanotechnology, Год журнала: 2025, Номер 16, С. 195 - 215
Опубликована: Фев. 17, 2025
The human eye, with its remarkable resolution of up to 576 million pixels, grants us the ability perceive world astonishing accuracy. Despite this, over 2 billion people globally suffer from visual impairments or blindness, primarily because limitations current ophthalmic treatment technologies. This underscores an urgent need for more advanced therapeutic approaches effectively halt even reverse progression eye diseases. rapid advancement nanotechnology offers promising pathways development novel therapies. Notably, photothermal nanomaterials, particularly well-suited transparent tissues have emerged as a potential game changer. These materials enable precise and controllable therapy by manipulating distribution thermal field. Moreover, they extend beyond conventional boundaries therapy, achieving unparalleled effects through their diverse composite structures demonstrating enormous in promoting retinal drug delivery photoacoustic imaging. paper provides comprehensive summary structure-activity relationship between properties these nanomaterials innovative mechanisms. We review latest research on nanomaterial-based treatments various Additionally, we discuss challenges future perspectives this field, focus enhancing global health.
Язык: Английский
Процитировано
0
Diagnostics, Год журнала: 2025, Номер 15(6), С. 659 - 659
Опубликована: Март 8, 2025
Background/Objectives: This study explores the micro-structure of celiac ganglia using two-photon microscopy (TPM) to highlight histological features in neurodegenerative conditions. Neurodegenerative diseases like Parkinson’s disease (PD) are linked dysautonomia, impacting autonomic regulation and leading significant gastrointestinal symptoms. Our research compares imaging results from TPM SHG microscopy, visualizing neuronal integrity, collagen distribution, architectural organization ganglia. specifically allows detailed fibers structures, revealing alterations density that correlate with dysautonomia. Methods: The cross-sectional was conducted at “Dr. Carol Davila” Central Military Emergency University Hospital, Bucharest, Romania, involving 70 participants diagnosed PD (Hoehn Yahr stages 2–4), including 35 dysautonomia without. We utilized samples patients without applying immunohistochemical markers for sympathetic neurons. Results: findings reveal pathological changes structure architecture. Immunohistochemical (neuropeptide Y, neurofilament heavy chain (NF-H), tyrosine hydroxylase) were employed characterize neurons, while provided high-resolution integrity extracellular matrix composition. Conclusions: These techniques present a promising tool early diagnosis assessment neurodegeneration patients. Moreover, these may represent critical bridge between histopathological clinical manifestations, underscoring their role enhancing our understanding dysfunction disease.
Язык: Английский
Процитировано
0
Journal of Controlled Release, Год журнала: 2024, Номер 377, С. 716 - 734
Опубликована: Дек. 3, 2024
Язык: Английский
Процитировано
1