Recent advances in the medical applications of two-dimensional MXene nanosheets
Nanomedicine,
Год журнала:
2024,
Номер
unknown, С. 1 - 22
Опубликована: Ноя. 18, 2024
MXene-based
materials
are
gaining
significant
attention
due
to
their
exceptional
properties
and
adaptability,
leading
diverse
advanced
applications.
In
3D
printing,
MXenes
enhance
the
performance
of
photoblockers,
photocurable
inks,
composites,
enabling
creation
precise,
flexible
durable
structures.
MXene/siloxane
composites
offer
both
flexibility
resilience,
while
MXene/spidroin
scaffolds
provide
excellent
biocompatibility
mechanical
strength,
making
them
ideal
for
tissue
engineering.
Sustainable
inks
such
as
MXene/cellulose
nano
alginate/MXene
MXene/emulsion
underscore
role
in
high-performance
printed
materials.
cancer
therapy,
enable
innovative
photothermal
photodynamic
therapies,
where
nanosheets
generate
heat
reactive
oxygen
species
destroy
cells.
MXene
theranostic
nanoprobes
combine
imaging
treatment,
MXene/niobium
support
hyperthermia
therapy
hydrogels
allow
controlled
drug
release.
Additionally,
nanozymes
catalytic
activity,
MXene/gold
nanorods
near-infrared-triggered
release
noninvasive
treatments.
antimicrobial
applications,
material
durability
hygiene,
providing
anticorrosive
protection
metals.
For
instance,
MXene/graphene,
MXene/polycaprolactone
nanofibers
MXene/chitosan
exhibit
antibacterial
activity.
sensors
have
been
developed
detect
antibiotic
residues.
cryogels
also
promote
regeneration,
nanohybrids
facilitate
photocatalytic
therapy.
These
advancements
potential
regenerative
medicine
other
fields.
Язык: Английский
Emerging Applications of Smart Hydrogel Nanocomposites in 3D Printing
Polymers for Advanced Technologies,
Год журнала:
2024,
Номер
35(12)
Опубликована: Дек. 1, 2024
ABSTRACT
This
review
provides
a
comprehensive
overview
of
the
emerging
applications
stimuli‐responsive
hydrogels
in
3D
printing,
emphasizing
their
transformative
potential
creating
adaptive
and
multifunctional
structures.
Stimuli‐responsive
hydrogels,
including
magneto‐,
thermo‐,
pH‐,
moisture‐,
solvent‐,
photo‐responsive
varieties,
have
gained
significant
attention
due
to
ability
undergo
dynamic
changes
response
specific
environmental
stimuli.
The
begins
by
exploring
fundamental
characteristics
fabrication
methods
used
additive
manufacturing,
highlighting
exceptional
adaptability
programmability.
It
then
delves
into
various
across
diverse
fields,
soft
robotics,
tissue
engineering,
drug
delivery
systems,
wearable
electronics,
food
technology,
electromagnetic
interference
shielding,
anti‐counterfeiting
technologies.
By
integrating
latest
advancements
printing
techniques,
this
aims
offer
insights
how
are
enabling
development
innovative,
intelligent,
environmentally
responsive
systems.
future
perspectives
section
discusses
challenges
opportunities
for
advancing
use
suggesting
directions
research
that
could
push
boundaries
functional
materials
programmable
Язык: Английский
Nature-Inspired Healing: Biomimetic Nanomaterials for Advanced Wound Management
Materials Today Sustainability,
Год журнала:
2024,
Номер
28, С. 100975 - 100975
Опубликована: Сен. 6, 2024
Язык: Английский
Research progress on MXenes in polysaccharide-based hemostasis and wound healing: A review
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
303, С. 140613 - 140613
Опубликована: Фев. 1, 2025
Язык: Английский
Near-infrared light-responsive nanocomposite hydrogels loaded with epidermal growth factor for diabetic wound healing
Materials Today Bio,
Год журнала:
2025,
Номер
31, С. 101578 - 101578
Опубликована: Фев. 14, 2025
In
diabetic
wounds,
the
presence
of
hyperglycemia
is
often
accompanied
by
a
persistent
inflammatory
response,
oxidative
stress
damage,
impaired
angiogenesis
and
bacterial
infections
around
wound,
resulting
in
proliferation
dermal
epidermal
cells
skin
regeneration
wounds.
To
solve
above
problems,
this
study
designed
near-infrared
(NIR)
light-responsive
multifunctional
poloxamer
hydrogel
(EGF/PDA-MXene
Gel).
The
Gel
composed
two-dimensional
nanomaterials
(2D
NMs)
MXene
as
core,
modified
polymer,
further
loaded
with
growth
factor
(EGF),
has
antibacterial,
antioxidant,
photothermal
properties.
Meanwhile,
EGF/PDA-MXene
can
be
used
drug
repository,
alleviating
problem
short
half-life,
realizing
sustained
release
EGF.
NIR
property
induces
protein
denaturation
leading
to
death
pathogenic
bacteria,
avoiding
common
clinical
antibiotic
resistance.
addition,
promotes
chronic
wound
healing
promoting
regeneration,
collagen
deposition,
angiogenesis,
several
other
mechanisms.
Therefore,
preparation
strategies
that
combine
bioactive
molecules
2D
NMs,
which
maintains
activity
EGF
while
exploiting
antimicrobial
advantages
NMs
photothermally,
provide
new
promising
therapeutic
approach
for
accelerating
repair
infected
Язык: Английский
Technological Aspects of MXenes: Current Challenges and Future Perspectives
Clean Energy Production Technologies,
Год журнала:
2025,
Номер
unknown, С. 233 - 247
Опубликована: Янв. 1, 2025
Язык: Английский
MXenes in the application of diabetic foot: mechanisms, therapeutic implications and future perspectives
Zhang Mengru,
Wu Qinyi,
Yao Zimo
и другие.
Journal of Materials Science Materials in Medicine,
Год журнала:
2025,
Номер
36(1)
Опубликована: Май 15, 2025
Язык: Английский
Carboxymethyl Chitosan Delaminated Ti3C2 MXenes as a Potential Therapeutic Nano Platform to Combat Chronic Wounds
Chemistry - An Asian Journal,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 29, 2025
Abstract
The
present
study
introduces
carboxymethyl
chitosan
(CMC)
delaminated
Ti
3
C
2
MXene
(MX_CMC)
as
a
novel
therapeutic
nanoplatform
for
chronic
wound
treatment.
was
with
CMC
in
water.
Electron
microscopy
confirmed
the
2D
layered
structure
of
MX_CMC,
which
demonstrated
60%
higher
dispersibility
aqueous
media
compared
to
MX
alone.
showed
high
cytocompatibility
human
adult
dermal
fibroblasts
(HADF)
and
positively
impacted
cell
migration,
fibroblast
differentiation,
VEGF
expression.
In
vitro
tube
formation
umbilical
vascular
endothelial
cells
(HUVEC)
further
angiogenic
nature
MX_CMC.
A
low
expression
proinflammatory
cytokines
(IL‐6
TNF‐α)
U937
line
upon
treatment
MX_CMC
implied
non‐immunogenic
material.
significant
antimicrobial
activity
against
S.
aureus
B.
subtilis
,
including
biofilm
prevention.
vivo
testing
rat
model
infected
diabetic
wounds
yielded
promising
outcomes.
this
study,
we
have
successfully
prepared
an
environment‐friendly
way,
not
only
exhibits
long‐term
biologically
relevant
media,
but
also
possesses
excellent
antimicrobial,
angiogenic,
anti‐inflammatory,
healing
properties.
conclusion,
could
be
potential
multifunctional
biomedical
applications,
especially
healing.
Язык: Английский
Isolation of Biomolecules Using MXenes
Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 11, 2024
Biomolecule
isolation
is
a
crucial
process
in
diverse
biomedical
and
biochemical
applications,
including
diagnostics,
therapeutics,
research,
manufacturing.
Recently,
MXenes,
novel
class
of
two-dimensional
nanomaterials,
have
emerged
as
promising
adsorbents
for
this
purpose
due
to
their
unique
physicochemical
properties.
These
biocompatible
antibacterial
nanomaterials
feature
high
aspect
ratio,
excellent
conductivity,
versatile
surface
chemistry.
This
timely
review
explores
the
potential
MXenes
isolating
wide
range
biomolecules,
such
proteins,
nucleic
acids,
small
molecules,
while
highlighting
key
future
research
trends
innovative
applications
poised
transform
field.
provides
an
in-depth
discussion
various
synthesis
methods
functionalization
techniques
that
enhance
specificity
efficiency
biomolecule
isolation.
In
addition,
mechanisms
by
which
interact
with
biomolecules
are
elucidated,
offering
insights
into
selective
adsorption
customized
separation
capabilities.
also
addresses
recent
advancements,
identifies
existing
challenges,
examines
emerging
may
drive
next
wave
innovation
rapidly
evolving
area.
Язык: Английский