Strategies and Advances in the Biomimetic Synthesis of Natural Products DOI Creative Commons
Lijun Hu,

Zhi‐Zhang Duan,

Ying Wang

и другие.

Engineering, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

Enzymatic ester bond formation strategies in fungal macrolide skeletons DOI

Jinmei Zhang,

Guanyin Yuan,

Yi Zou

и другие.

Natural Product Reports, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

This review mainly focuses on the essential roles of thioesterase and condensation domains in fungal macrolide biosynthesis their chemoenzymatic applications. It also discusses differences ester bond formation between fungi bacteria.

Язык: Английский

Процитировано

0
The Croton genera (Euphorbiaceae) and its richness in chemical constituents with potential range of applications DOI Creative Commons
Carlos Andrés Coy Barrera,

Laura Galvis,

M. Rueda

и другие.

Phytomedicine Plus, Год журнала: 2025, Номер unknown, С. 100746 - 100746

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Potential mechanism of traditional Chinese medicine intervention in gastric cancer: targeted regulation of autophagy DOI Creative Commons

Siyuan Sun,

Wenqian Yu,

Guangheng Zhang

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Фев. 18, 2025

Gastric cancer (GC) is a prevalent malignant tumor that originates from the epithelial cells of gastric mucosa, predominantly in form adenocarcinoma. Extensive research has confirmed significant role autophagy initiation, progression, and chemoresistance GC. The potential traditional Chinese medicine (TCM) to exert anti-tumor effects by modulating been demonstrated, particularly context GC prevention treatment. Natural products (NPs) have great therapeutic treatment targeting autophagy-related genes signaling pathways intervene biological behaviors such as proliferation, metastasis, invasion death. This article describes molecular mechanisms key markers autophagy, involved GC-associated (PI3K/AKT/mTOR, AMPK, MAPK, p53), summarizes mechanism Helicobacter pylori infection GC, how interacts with apoptotic iron-death processes wide-ranging influences these factors play process. Finally, this paper systematically natural compounds terpenoids, polyphenols, alkaloids, saponins, polysaccharides modulate targets for evaluates toxic NPs, providing more compelling rationale direction therapy.

Язык: Английский

Процитировано

0
DCTPP1: A promising target in cancer therapy and prognosis through nucleotide metabolism DOI
Shaoxuan Liu, Feng Li, Zhe Wang

и другие.

Drug Discovery Today, Год журнала: 2025, Номер unknown, С. 104348 - 104348

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Discovery of new 1,2,3,4-tetrahydro-β-carboline derivatives decorated with 3-N-substituted propionyl moiety flexibly bridged-chain as reactive oxygen species inducer for efficient antibacterial treatment DOI
Yike Yang, Shanshan Su,

Zhaoju Sun

и другие.

Bioorganic Chemistry, Год журнала: 2025, Номер 160, С. 108473 - 108473

Опубликована: Апрель 14, 2025

Язык: Английский

Процитировано

0
A novel liver-targeted and highly selective fluorescent probe for hepatic hydrogen sulfide detection in the diagnosis of drug-induced liver injury DOI
Yalin Li, Bing Liao, Qunyou Tan

и другие.

European Journal of Medicinal Chemistry, Год журнала: 2025, Номер unknown, С. 117640 - 117640

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Bioactive Matters based on Natural Product for Cardiovascular Diseases DOI Creative Commons
L. Zhong,

Xiaoying Tan,

Wenhui Yang

и другие.

Smart Materials in Medicine, Год журнала: 2024, Номер 5(4), С. 542 - 565

Опубликована: Ноя. 16, 2024

Язык: Английский

Процитировано

0
Strategies and Advances in the Biomimetic Synthesis of Natural Products DOI Creative Commons
Lijun Hu,

Zhi‐Zhang Duan,

Ying Wang

и другие.

Engineering, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

0