Chemo‐, Regio‐ and Stereoselective Preparation of (Z)‐2‐Butene‐1,4‐Diol Monoesters via Pd‐Catalyzed Decarboxylative Acyloxylation DOI
Cheng Long,

Jiali Zhao,

Xiaotian Zhang

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 30(39)

Опубликована: Май 13, 2024

(Z)-alkenes are useful synthons but thermodynamically less stable than their (E)-isomers and typically more difficult to prepare. The synthesis of 1,4-hetero-bifunctionalized is particularly challenging due the inherent regio- stereoselectivity issues. Herein we demonstrate a general, chemoselective direct (Z)-2-butene-1,4-diol monoesters. protocol operates within Pd-catalyzed decarboxylative acyloxylation regime involving vinyl ethylene carbonates (VECs) various carboxylic acids as reaction partners under mild operationally attractive conditions. newly developed process allows access structurally diverse pool monoesters in good yields with excellent stereoselectivity. Various synthetic transformations obtained how these great use rapidly diversify portfolio formal desymmetrized (Z)-alkenes.

Язык: Английский

Diverse Catalytic Applications of Phosphine Oxide‐Based Metal Complexes DOI
Ashish Anand,

S. Perinbanathan,

Indresh Singh

и другие.

ChemCatChem, Год журнала: 2024, Номер 16(22)

Опубликована: Авг. 17, 2024

Abstract Phosphine oxides are an interesting class of compounds possessing tetracoordinate and pentavalent phosphorus atoms have been employed in a wide range applications including reagents organic synthesis, metal extractants, flame retardants, pharmaceuticals, bioactivity studies. Among all, the degree basicity phosphoryl oxygen driven by nature substituents influences electronic properties central complex toward diversified catalytic processes. Further, presence heteroatoms adjacent to atom enhances nucleophilicity atom. In view this, present review covers past two decades remarkable versatility P=O‐based complexes describes governing factors influencing structural resultant coordination behavior. Interestingly, some P=O bond distances either longer or shorter compared their free ligands, indicating activity. These can effectively catalyze chemical reactions polymerizations, C−C Si−C activations, oxidation, reduction, hydroformylation, hydrophosphination, hydrogenation cyclization reactions. Furthermore, this emphasizes impact substituents, solvents, additives, light, temperature on efficiency.

Язык: Английский

Процитировано

1

Chemo‐, Regio‐ and Stereoselective Preparation of (Z)‐2‐Butene‐1,4‐Diol Monoesters via Pd‐Catalyzed Decarboxylative Acyloxylation DOI
Cheng Long,

Jiali Zhao,

Xiaotian Zhang

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 30(39)

Опубликована: Май 13, 2024

(Z)-alkenes are useful synthons but thermodynamically less stable than their (E)-isomers and typically more difficult to prepare. The synthesis of 1,4-hetero-bifunctionalized is particularly challenging due the inherent regio- stereoselectivity issues. Herein we demonstrate a general, chemoselective direct (Z)-2-butene-1,4-diol monoesters. protocol operates within Pd-catalyzed decarboxylative acyloxylation regime involving vinyl ethylene carbonates (VECs) various carboxylic acids as reaction partners under mild operationally attractive conditions. newly developed process allows access structurally diverse pool monoesters in good yields with excellent stereoselectivity. Various synthetic transformations obtained how these great use rapidly diversify portfolio formal desymmetrized (Z)-alkenes.

Язык: Английский

Процитировано

0