Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 29, 2025

The efficient synthesis of trisubstituted trivalent phosphines remains challenging. Herein, we report a novel approach for rapid construction these compounds from aldehydes under Lewis acid-mediated conditions. By using sterically hindered disubstituted phosphines, can undergo deoxygenative reaction to afford phosphorus compounds. This modular and practical method is characterized by operational simplicity, broad substrate scope, excellent functional group tolerance, which holds great potential applications in organic synthesis.

Язык: Английский