tert‐Butyl Nitrite‐Mediated Deaminative Chalcogenation of Substituted 5‐Aminopyrazoles via Diaryl Dichalcogenides DOI

Farman Moh Abbasi,

Aritra Ghosh,

Ruchir Kant

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(21)

Опубликована: Май 31, 2025

Abstract An expedited route to the synthesis of substituted 5‐(arylselanyl)‐1 H ‐pyrazoles and 5‐(arylthio)‐1 via reaction between 5‐amino‐1 bearing an electron withdrawing group (EWG) at C‐4 diaryl dichalcogenides in presence tert ‐butyl nitrite is described. The protocol compatible with substrates different EWGs, such as carboxylate, nitrile or phenylsulfonyl. strategy works even ‐1,2,3‐triazoles furnish corresponding chalcogenides. mechanism postulated involve a radical pathway.

Язык: Английский

tert‐Butyl Nitrite‐Mediated Deaminative Chalcogenation of Substituted 5‐Aminopyrazoles via Diaryl Dichalcogenides DOI

Farman Moh Abbasi,

Aritra Ghosh,

Ruchir Kant

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(21)

Опубликована: Май 31, 2025

Abstract An expedited route to the synthesis of substituted 5‐(arylselanyl)‐1 H ‐pyrazoles and 5‐(arylthio)‐1 via reaction between 5‐amino‐1 bearing an electron withdrawing group (EWG) at C‐4 diaryl dichalcogenides in presence tert ‐butyl nitrite is described. The protocol compatible with substrates different EWGs, such as carboxylate, nitrile or phenylsulfonyl. strategy works even ‐1,2,3‐triazoles furnish corresponding chalcogenides. mechanism postulated involve a radical pathway.

Язык: Английский

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