A photocatalytic method for the generation of the 1,1,1,3,3,3-hexafluoroisopropyl radical
Sergey S. Lunkov,
Vladislav S. Kostromitin,
Artem A. Zemtsov
и другие.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(17), С. 4762 - 4768
Опубликована: Янв. 1, 2024
A
method
for
the
generation
of
hexafluoroisopropyl
radical
by
photoredox
cleavage
C,O
bond
is
described.
The
key
reagent
obtained
from
hexafluoroisopropanol.
Язык: Английский
Sodium Hypophosphite as a Halogen Atom Transfer (XAT) Agent under Photocatalytic Conditions
Ekaterina V. Malakhova,
Vladislav S. Kostromitin,
Demian Y. Cheboksarov
и другие.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(17), С. 12812 - 12821
Опубликована: Авг. 9, 2024
The
ability
of
sodium
hypophosphite
to
generate
the
phosphorus-centered
radical,
which
can
activate
carbon–halogen
bond
via
halogen
atom
transfer
(XAT)
is
described.
hydroalkylation
nonactivated
alkenes
with
methyl
bromoacetate
was
performed
using
as
reducing
agent
under
photocatalytic
conditions.
key
phosphorus
centered
radical
formed
from
anion
by
hydrogen
abstraction.
Язык: Английский
Photocatalytic Hydrodichloromethylation of Unactivated Alkenes with Chloroform
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 16, 2024
A
visible-light-induced
method
for
the
hydrodichloromethylation
of
unactivated
alkenes
using
chloroform
(CHCl3)
was
developed,
employing
pyridine·BH3
as
halogen
atom
transfer
(XAT)
reagent.
The
strategy
showed
a
broad
functional
group
tolerance,
and
29
examples
alkenes,
including
complex
natural
products
or
drug
derivatives,
have
been
established
with
good
yields.
Mechanistic
studies
indicated
that
CHCl3
serves
both
source
dichloromethyl
radical
hydrogen
(HAT)
reagent,
borane
short-chain
reaction
process
involved
in
this
system.
This
represents
novel
approach
without
an
additional
HAT
Язык: Английский