
Molecules, Год журнала: 2025, Номер 30(8), С. 1669 - 1669
Опубликована: Апрель 8, 2025
Chelation-assisted olefinic C-H functionalization has been demonstrated to be a powerful method of constructing multi-substituted alkenes from simpler ones. This strategy produces complex in regio- and stereoselective manner, followed by endo- exo-cyclometallation. Among the various directing groups developed, N,N- N,O-bidentate are most widely used selectively promote due their fine, tunable, reversible coordination with metal center. In this review, we discuss group-assisted bond reactions, including alkenylation, alkylation, arylation, thiolation, silylation, halogenation, cyclization.
Язык: Английский