Chinese Journal of Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Май 27, 2025

Comprehensive Summary An innovative approach to synthesizing pyrrole‐functionalized phosphorodithioates via a copper‐catalyzed cascade phosphorodithiolation/cyclization of β‐ketodinitriles is disclosed. This method employs tetraphosphorus decasulfide (P 4 S 10 ) as phosphorus source, activated by alcohols under mild conditions. A wide range and are well‐tolerated, affording the desired products with good excellent yields, underscoring broad functional group compatibility. Notably, this process eschews need for noble metal catalysts, aligning green chemistry principles enabling direct sustainable transformation from inorganic organic phosphorus. Furthermore, synthesized demonstrate potent antibacterial properties against Staphylococcus aureus .

Язык: Английский