Advances in Coordination Chemistry of Schiff Base Complexes: A Journey from Nanoarchitectonic Design to Biomedical Applications

Topics in Current Chemistry, Год журнала: 2025, Номер 383(1)

Опубликована: Фев. 3, 2025

Язык: Английский

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Hydrazones, hydrazones-based coinage metal complexes, and their biological applications

RSC Advances, Год журнала: 2025, Номер 15(8), С. 6191 - 6207

Опубликована: Янв. 1, 2025

Hydrazone-based compounds distinguished by their azomethine –NHNCH group and respective coinage metal complexes have emerged as leading candidates in the search for effective anticancer antibiotic agents.

Язык: Английский

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Recent advances of Schiff base metal complexes as potential anticancer agents

Coordination Chemistry Reviews, Год журнала: 2024, Номер 525, С. 216327 - 216327

Опубликована: Ноя. 20, 2024

Язык: Английский

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Investigation on Cytotoxicity Against Lung Carcinoma Cell Line at New Metallacyclic Complexes of Titanium(IV) Incorporated With β‐Diketone and 4‐(1,4,5‐Triphenyl‐1H‐Imidazol‐2‐Yl) Benzene‐1,2‐Diol Derivatives

Applied Organometallic Chemistry, Год журнала: 2025, Номер 39(6)

Опубликована: Май 25, 2025

ABSTRACT A series of eight heteroleptic derivatives titanium(IV) has been synthesized and characterized systematically employing physico‐chemical methods. Derivatives Ti 1 [(C 37 H 32 N 2 O 6 )Ti], 38 34 3 31 FN 4 ClN 5 BrN 8 7 F )Ti] were developed by refluxing an anhydrous benzene solution Ti(OPr i ) , acetylacetone, appropriate bidentate ligands (L ‑L in 1:2:1 stoichiometry. The electronic structure properties complexes (Ti ‑Ti studied density functional theory (DFT). UV–Visible method was used to determine the stability at periodic intervals. Binding interactions bovine serum albumin (BSA) calf thymus DNA (CT‐DNA) with corresponding assessed spectroscopic techniques such as absorption, fluorescence, circular dichroism have established intercalation static quenching for BSA effective manner. docking investigations also revealed that ‐Ti are well engaged via intercalative mode favorably occupy active site protein through hydrogen bonding. Furthermore, cytotoxicity against A549 (lung carcinoma) cell lines MTT (methylthiazolyldiphenyl‐tetrazolium) assay, IC 50 values found be range from 16.77 75.60 μM. displayed significant apoptosis induced cycle arrest G phase line.

Язык: Английский

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Metal-based compounds: Synthesis and characterization of new thiazole-based iridium and palladium complexes with potential anticancer and other biological activities

Polyhedron, Год журнала: 2024, Номер 263, С. 117211 - 117211

Опубликована: Авг. 30, 2024

Язык: Английский

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Cadmium and silver complexes of a pyridine containing ligand: syntheses, structural studies, biological activity and docking studies

RSC Advances, Год журнала: 2024, Номер 14(43), С. 31850 - 31860

Опубликована: Янв. 1, 2024

Novel complexes of Cd( ii ) and Ag( i derived from TPT ligand have been synthesized. The silver showed great potential as a therapeutic candidate for treating breast cancer.

Язык: Английский

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