Magnetic Properties, Heat Generation, and Apatite Formation Ability of Mg‐Ti Ferrite Particles Synthesized by Solid‐State Reaction and Polymerized Complex Methods

Advanced Engineering Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 13, 2025

Titanium‐doped ferrite has garnered significant interest as thermoseeds for cancer hyperthermia because of its controllable Curie point near body temperature, which prevents overheating and ensures high biological safety. However, few studies examine the effect synthesis conditions on microstructure, magnetic properties, heat generation in an alternating field. Herein, Mg 1+ x Fe 2−2 Ti O 4 ( = 0.35, 0.45) particles are synthesized by a solid‐state reaction polymerized complex methods, followed sintering at various temperatures. Their properties behavior field investigated. Particles with 0.45 generate significantly less than those despite both being single‐phase ferrite. method temperature 1200 °C exhibit lower saturation magnetization but higher increases compared method. Additionally, range 800–1000 °C, increase more 10 is observed method, likely result inclusion highly crystalline superparamagnetic particles. Furthermore, form bone‐like apatite their surface simulated fluid, suggesting potential novel material combining bone integration properties.

Язык: Английский

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Potential Molecular Interactions and In Vitro Hyperthermia, Thermal, and Magnetic Studies of Bioactive Nickel-Doped Hydroxyapatite Thin Films

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(3), С. 1095 - 1095

Опубликована: Янв. 27, 2025

The treatment of bone cancer often necessitates the surgical removal affected tissues, with artificial implants playing a critical role in replacing lost structure. Functionalized represent an innovative approach to improve bio-integration and long-term effectiveness surgery treating cancer-damaged bones. In this study, nickel-substituted hydroxyapatite (Ni:HAp) nanoparticles were deposited as thin films using laser pulses range 30,000–60,000. Comprehensive structural, infrared, optical, morphological, surface, magnetic evaluations conducted on synthesized Ni:HAp films. hysteresis (M-H) loop demonstrated increase saturation magnetization higher number pulses. A minimum squareness ratio 0.7 was observed at 45,000 pulses, M-H characteristics indicated shift toward ferromagnetic behavior, achieving desired thermal response through alternating field application within 80 s. Thermogravimetric analysis revealed distinct stability, material structure exhibiting 46% degradation 800 °C. incorporation bioactive film holds significant promise for hyperthermia treatment. Using HDOCK simulations, interactions between ligand molecules proteins also explored. Strong binding affinities docking score −67.73 thus observed. presence Ca2+ ions enhances electrostatic interactions, providing valuable insights into biochemical roles therapeutic applications. Intravenous administration nanoparticles, which subsequently aggregate tumor tissue, combined applied field, enable targeted heating 45 This focused selectively targets cells while preserving surrounding healthy thereby potentially enhancing therapy

Язык: Английский

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Functional mixed metal oxide nanomaterials: a comprehensive review of their hyperthermic potential in cancer therapy

New Journal of Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

This review provides a comprehensive and well-structured analysis of magnetic hyperthermia therapy (MHT) as potential cancer treatment.

Язык: Английский

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Next‐Generation Flexible Embolic Systems: Targeted Transarterial Chemoembolization Strategies for Hepatocellular Carcinoma

Advanced Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 7, 2025

Abstract Transarterial chemoembolization (TACE) remains the gold standard for treating intermediate‐stage hepatocellular carcinoma (HCC), yet faces great challenges in overcoming tumor heterogeneity, hypoxia‐induced angiogenesis, and metastatic progression. The development of advanced flexible embolization materials marks a revolutionary leap interventional therapy, offering opportunities to revolutionize precision, drug delivery kinetics, microenvironment modulation. This comprehensive review systematically examines paradigm shift toward next‐generation TACE technology, emphasizing limitations conventional approaches innovations embolic agents. A detailed discussion nano‐flexible systems is presented, their unique coagulation dynamics, real‐time imaging capabilities, therapeutic precision. delves into groundbreaking strategies integrating hypoxia modulation, energy conversion therapeutics, sophisticated engineering. Clinical translation aspects are thoroughly explored, including large‐scale trial outcomes, vascular recanalization patient‐specific treatment optimization. Looking forward, key frontiers field identified: intelligent nanocomposite systems, synergistic combination therapies, precision medicine tailored individual biology. work not only objectively evaluates current progress but also charts future research priorities, aiming transform from palliative intervention platform ultimately reshaping landscape HCC patient care.

Язык: Английский

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Vacuum ambient exploration of temperature-driven dielectric relaxation and magnetic dynamics in Mn2+ substituted ZnFe2O4 nano spinel ferrites

Materials Science and Engineering B, Год журнала: 2025, Номер 318, С. 118317 - 118317

Опубликована: Апрель 14, 2025

Язык: Английский

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Exploring Calcium Phosphate-Based Magnetic Nanofluids as Nanoheater: Insights into Magnetic Hyperthermia Application

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 25, 2025

Язык: Английский

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Effect of Dual-Doped Hydroxyapatite Nanoparticles Loaded with 5-Fluorouracil on Breast Cancer Treatment Through the Disruption of DNA Replication: In Vitro Drug Release and Kinetics Study

BioNanoScience, Год журнала: 2024, Номер 15(1)

Опубликована: Дек. 18, 2024

Язык: Английский

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