Wound dressings using electrospun nanofibers: mechanisms, applications, and future directions

European Polymer Journal, Год журнала: 2025, Номер unknown, С. 113900 - 113900

Опубликована: Март 1, 2025

Язык: Английский

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Advances in Bacterial Cellulose‐Based Scaffolds for Tissue Engineering: Review

Journal of Biomedical Materials Research Part A, Год журнала: 2025, Номер 113(4)

Опубликована: Апрель 1, 2025

ABSTRACT Bacterial cellulose (BC) has emerged as a highly versatile and promising biomaterial in tissue engineering, with potential applications across skin, bone, cartilage, vascular regeneration. Its exceptional properties like high mechanical strength, superior biocompatibility, excellent moisture retention, inherent ability to support cell adhesion proliferation, make BC particularly effective for wound healing skin These attributes accelerate repair foster new formation, highlighting its value skin‐related applications. Additionally, BC's capacity osteogenic differentiation, combined robustness, positions it strong candidate bone facilitating regeneration repair. Recent advancements have emphasized the development of BC‐based hybrid scaffolds enhance tissue‐specific functionalities, including vascularization cartilage innovations aim address complex requirements various engineering However, challenges remain, regarding scalability production, cost‐effectiveness, long‐term stability scaffolds. Such barriers continue limit broader clinical adoption. This review critically examines synthesis methods, intrinsic properties, recent design scaffolds, offering insights into their revolutionize regenerative medicine. Furthermore, addresses key limitations that must be overcome enable integration BC. By addressing these limitations, could play transformative role advancing therapies, bridging gap between laboratory research application.

Язык: Английский

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Novel Estimation of Nanofiber Diameter from SEM Images Using Deep Feature Embeddings and Machine Learning Models

Advanced Theory and Simulations, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

Abstract Accurate nanofiber diameter estimation is crucial for optimizing their functionality in materials science. Traditional measurement methods from Scanning Electron Microscopy (SEM) images are often labor‐intensive and subjective. This study proposes a machine learning‐based approach using deep feature embeddings to predict average diameters directly SEM images. Eight learning models—Linear Regression (LR), k‐Nearest Neighbors (kNN), Decision Tree (DT), Random Forest (RF), Support Vector Machine (SVM), Neural Network (NN), Gradient Boosting (GB), AdaBoost—are evaluated 5‐fold 10‐fold cross‐validation. Performance assessed via Mean Squared Error (MSE), Root (RMSE), Absolute (MAE), Percentage (MAPE), R 2 . The kNN model consistently outperformed others across three datasets: smooth nanofibers, beaded combined set. It achieves the lowest error metrics highest (0.950) while demonstrating strong generalization morphologies. among first integrate with direct prediction, providing reliable alternative traditional methods.

Язык: Английский

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Use of electrospun chia seed mucilage nanofibers rich in biopolymers in encapsulation of Hypericum perforatum extract

Carbohydrate Polymer Technologies and Applications, Год журнала: 2025, Номер unknown, С. 100813 - 100813

Опубликована: Апрель 1, 2025

Язык: Английский

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Preparation and properties of a novel alginate/carrageenan crosslinked coordination polymer and evaluation of the antibacterial, antioxidant and anticancer potential of its Co(ii), and Cr(iii) polymeric complexes

RSC Advances, Год журнала: 2024, Номер 14(52), С. 38934 - 38943

Опубликована: Янв. 1, 2024

Natural polysaccharides play a crucial role across diverse fields such as medicine, food, and cosmetics, for their various physiochemical biological properties. In this study, we developed new crosslinked biopolymer using sodium alginate (AG) carrageenan (CAR) polysaccharides. Various metal complexes involving different salts CoCl

Язык: Английский

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Electrospun-based nanofibers as ROS-scavenging scaffolds for accelerated wound healing: a narrative review

International Journal of Polymeric Materials, Год журнала: 2024, Номер unknown, С. 1 - 33

Опубликована: Дек. 16, 2024

This review delves into the efficacy of electrospun nanofibers as structures capable neutralizing Reactive Oxygen Species (ROS), thereby aiding in acceleration wound repair. ROS occupy a dual position cellular dynamics, being indispensable for intracellular communication, yet they potentially exacerbate oxidative stress which can stall healing trajectory. The method electrospinning synthesizes distinguished by their expansive surface area relative to volume and notable porosity, rendering them optimally suited medical endeavors, particularly frameworks that bolster recuperation. analysis elucidates diverse roles these play, from enhancing clot formation combating microbial invasion mitigating inflammation, fostering proliferation, facilitating angiogenesis—each pivotal component effective mending wounds.

Язык: Английский

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