Visible-light-mediated site-selective C(sp2)–H alkylation of tropones facilitates semi-synthesis of cephafortunoids A and B DOI Creative Commons
Q. Zeng, Cheng‐Yu Zheng,

Zhan‐Peng Ge

и другие.

Chemical Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

An efficient visible-light-driven method for achieving α-site-selective C–H alkylation of tropones was developed. It applied to transform fortunolide A into cephafortunoids and B, marking the first synthesis C 20 Cephalotaxus troponoids.

Язык: Английский

Gold-Catalyzed Difunctionalization of Activated Alkynes with Organohalides: Access to 3-Arylated and Alkenylated Coumarin Derivatives DOI

Yu Zhong,

Yuanhao He,

Yan-Fei Hu

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Фев. 27, 2025

Coumarin skeletons are significant structural units frequently used in the fields of synthetic chemistry, medicinal and materials science. Herein, we report a hemilabile P,N-ligand-assisted gold-catalyzed difunctionalization activated alkynes with organohalides. The reaction occurs effectively under mild conditions without requiring an external oxidant, producing variety 3-arylated alkenylated coumarin derivatives high to excellent yields. This method demonstrates wide substrate tolerance superb functional group compatibility is also suitable for heteroaromatic substrates. Further mechanistic investigations strongly support proposed mechanism reaction.

Язык: Английский

Процитировано

0
Rhodium(III)-catalyzed selective C−H olefination and desilylative vinylation of acyclic enamides with vinylsilanes DOI
Xiaolan Li, Jie Liu,

Ruixin Song

и другие.

Journal of Catalysis, Год журнала: 2025, Номер unknown, С. 116051 - 116051

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Catalyst-Free, Scalable, Green-Light-Mediated Iodoamination, and Further Transformation of Olefins Under Continuous Flow Conditions DOI Creative Commons

Viktor Klöpfer,

Leonie Roithmeier,

Manuel Kobras

и другие.

Organic Process Research & Development, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

Язык: Английский

Процитировано

0
Photocatalytic Iminothiolation of Alkenes via Monothiocarbonate Oxime Esters DOI
Ranjini Laskar,

Rebecca E. Thielemann,

Janosch Knüppe

и другие.

ACS Catalysis, Год журнала: 2025, Номер unknown, С. 6731 - 6738

Опубликована: Апрель 10, 2025

Язык: Английский

Процитировано

0
Visible-light-mediated site-selective C(sp2)–H alkylation of tropones facilitates semi-synthesis of cephafortunoids A and B DOI Creative Commons
Q. Zeng, Cheng‐Yu Zheng,

Zhan‐Peng Ge

и другие.

Chemical Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

An efficient visible-light-driven method for achieving α-site-selective C–H alkylation of tropones was developed. It applied to transform fortunolide A into cephafortunoids and B, marking the first synthesis C 20 Cephalotaxus troponoids.

Язык: Английский

Процитировано

0