Unveiling a carbazole-based photocatalyst for visible-light-driven synthesis of indolyl diarylmethanes and 2-benzimidazoles
Catalysis Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
carbazole-based
photocatalyst
(MD)
incorporating
a
dicyanovinyl
acceptor
and
exhibiting
superior
redox
potential
has
been
demonstrated
for
sustainable
photocatalytic
approach
to
synthesize
indolyl
diarylmethanes
2-substituted
benzimidazoles.
Язык: Английский
Manganese-Promoted Electrochemical Imino-Pinacol Coupling to Access Vicinal Diamines
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 5, 2025
We
herein
introduce
an
electrochemical
imino-pinacol
coupling
reaction
to
access
the
vicinal
diamine
scaffold.
This
green
and
convenient
protocol
employs
in
situ-generated
imines
as
starting
materials
deliver
a
broad
range
of
products
under
electroreductive
conditions.
Moreover,
this
is
also
applicable
pinacol
coupling.
Mechanistic
investigation
suggests
that
Mn(III)
additive
essential
for
promoting
SET
reduction
imine
material
preventing
formation
over-reduced
amine
side
product.
Язык: Английский
Visible‐Light‐Induced C−H Amidation of (Hetero)arenes with Hypervalent Iodine(III) Reagents
Asian Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 10, 2025
Abstract
A
visible‐light‐promoted
C−H
amidation
of
(hetero)arenes
with
hypervalent
iodine
reagents
has
been
successfully
achieved
good
yields.
The
high
efficiency,
broad
substrate
range
and
functional
group
compatibility
demonstrated
the
utility
method.
Moreover,
this
protocol
was
suitable
for
late‐stage
functionalization
natural
products.
Mechanistic
studies
have
shown
that
N‐centred
saccharin
radical
mediates
arenes.
Язык: Английский
Designing Peptide-Based Nucleophilic Catalysts Possessing Multiple Identical Active Sites for Late-Stage Chlorination of Peptides and Drugs
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 3, 2025
In
the
quest
for
developing
catalysts
with
multiple
active
sites,
we
designed
a
series
of
methionine-based
peptide
prepared
by
classical
coupling.
Given
widespread
presence
aromatic
chloro-substituents
and
their
significant
pharmacokinetic
properties,
performance
these
were
evaluated
late-stage
chlorination
tyrosine
residue
on
peptides
up
to
octamer
as
well
drug
molecules.
The
operationally
simple
reaction
conditions,
excellent
catalyst
loading
0.25
mol
%,
gram-scale
reactions
are
major
highlights
this
method.
Язык: Английский
Pyrene-Based Organic Photoredox Catalysts for Carbon–Carbon Bond-Forming Reactions: Reductive Coupling of Aromatic Carbonyl and Imine Compounds
Organic Letters,
Год журнала:
2024,
Номер
26(36), С. 7718 - 7722
Опубликована: Сен. 5, 2024
Metal-free
photoredox
catalysts
built
upon
a
pyrene
core
were
developed
for
carbon-carbon
bond-forming
reactions.
Among
these
catalysts,
derivative
containing
urea
moiety
effectively
facilitated
the
reductive
coupling
of
aromatic
carbonyl
and
imine
compounds
under
blue
LED
irradiation.
This
process
provided
corresponding
vicinal
diols
diamines
in
good
yields.
Язык: Английский
Dehydrogenative Photocyclization of 3-Styryl Indoles to Fused Indole Systems
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 7, 2024
The
synthesis
of
5-aryl-
or
5,6-diaryl-11
Язык: Английский
Intramolecular C–H arylation of pyridine derivatives with a palladium catalyst for the synthesis of multiply fused heteroaromatic compounds
Beilstein Journal of Organic Chemistry,
Год журнала:
2024,
Номер
20, С. 3256 - 3262
Опубликована: Дек. 13, 2024
The
C–H
arylation
of
2-quinolinecarboxyamide
bearing
a
C–Br
bond
at
the
N
-aryl
moiety
is
carried
out
with
palladium
catalyst.
reaction
proceeds
on
pyridine
ring
adjacent
to
amide
group
in
presence
10
mol
%
Pd(OAc)
2
110
°C
afford
cyclized
product
42%
yield.
yield
improved
94%
when
performed
PPh
3
as
ligand
palladium.
examined
amides
derived
from
unsubstituted
picoline,
6-methylpicoline,
and
2,6-pyridinedicarboxylic
acid
similar
manner
products
70%,
77%,
87%
yield,
respectively.
related
also
non-pyridine
derivatives
terephthal-
benzamides
multiply
fused
heterocyclic
compounds
81%
89%
yields,
Язык: Английский