Integrating Natural Product Research Laboratory with artificial intelligence: advancements and breakthroughs in traditional medicine DOI Creative Commons
Jai‐Sing Yang, Shih‐Chang Tsai, Yuan‐Man Hsu

и другие.

Biomedicine, Год журнала: 2024, Номер 14(4)

Опубликована: Дек. 1, 2024

The Natural Product Research Laboratory (NPRL) of China Medical University Hospital (CMUH) was established in collaboration with CMUH and Professor Kuo-Hsiung Lee from the North Carolina at Chapel Hill. laboratory collection features over 6,000 natural products worldwide, including pure compounds semi-synthetic derivatives. This is most comprehensive fully operational product database Taiwan. review article explores history development NPRL CMUH. We then provide an overview recent applications impact artificial intelligence (AI) new drug discovery. Finally, we examine advanced powerful AI-tools related software to explain how these resources can be utilized research on large-scale data libraries. presents a (R&D) platform that combines AI NPRL. believe this approach will reduce resource wastage enhance capabilities Taiwan's academic industrial sectors biotechnology pharmaceuticals.

Язык: Английский

Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment DOI

Jing-wen Guo,

Guo‐Qiang Lin,

Xinyi Tang

и другие.

Acta Pharmacologica Sinica, Год журнала: 2025, Номер unknown

Опубликована: Янв. 17, 2025

Язык: Английский

Процитировано

0

The Human Touch in Acupuncture: A Future with Artificial Intelligence? DOI Open Access
Gerhard Litscher

OBM Integrative and Complementary Medicine, Год журнала: 2025, Номер 010(01), С. 1 - 6

Опубликована: Янв. 7, 2025

Acupuncture, an ancient practice in traditional Chinese medicine, is founded on understanding of human physiology and the dynamics energy flow (Qi). The emergence artificial intelligence (AI) modern medicine presents opportunities to integrate advanced technologies into acupuncture, enhancing diagnostic precision empirical validation. AI tools can analyze complex datasets, model dynamics, provide evidence-based insights, potentially bridging methodologies with scientific paradigms. However, element, characterized by intuition, empathy, holistic decision-making, remains central effective treatment. This editorial explores transformative potential its limitations, importance preserving relational manual aspects practice. By fostering a synergistic relationship between practitioners, acupuncture advance as scientifically validated yet human-centered therapeutic modality. Ethical considerations balanced integration are imperative ensure that technological innovations complement rather than overshadow core values this healing art.

Язык: Английский

Процитировано

0

An AI-driven strategy for active compounds discovery and non-destructive quality control in traditional Chinese medicine: a case of Xuefu Zhuyu Oral Liquid DOI
Lele Gao, Liang Zhong, Tingting Feng

и другие.

Talanta, Год журнала: 2025, Номер unknown, С. 127627 - 127627

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Traditional Herbal Medicine Pithecellobium clypearia (Jack) Benth: Research progress in chemical constituents and pharmacological activities DOI

Dapeng Su,

Siqi Liu,

Chao-Geng Lyu

и другие.

Journal of Ethnopharmacology, Год журнала: 2025, Номер unknown, С. 119635 - 119635

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Artificial intelligence in traditional Chinese medicine: advances in multi-metabolite multi-target interaction modeling DOI Creative Commons
Li Yu, Xiangjun Liu, Jingwen Zhou

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Апрель 15, 2025

Traditional Chinese Medicine (TCM) utilizes multi-metabolite and multi-target interventions to address complex diseases, providing advantages over single-target therapies. However, the active metabolites, therapeutic targets, especially combination mechanisms remain unclear. The integration of advanced data analysis nonlinear modeling capabilities artificial intelligence (AI) is driving transformation TCM into precision medicine. This review concentrates on application AI in target prediction, including multi-omics techniques, TCM-specialized databases, machine learning (ML), deep (DL), cross-modal fusion strategies. It also critically analyzes persistent challenges such as heterogeneity, limited model interpretability, causal confounding, insufficient robustness validation practical applications. To enhance reliability scalability future research should prioritize continuous optimization algorithms using zero-shot learning, end-to-end architectures, self-supervised contrastive learning.

Язык: Английский

Процитировано

0

Integrating Natural Product Research Laboratory with artificial intelligence: advancements and breakthroughs in traditional medicine DOI Creative Commons
Jai‐Sing Yang, Shih‐Chang Tsai, Yuan‐Man Hsu

и другие.

Biomedicine, Год журнала: 2024, Номер 14(4)

Опубликована: Дек. 1, 2024

The Natural Product Research Laboratory (NPRL) of China Medical University Hospital (CMUH) was established in collaboration with CMUH and Professor Kuo-Hsiung Lee from the North Carolina at Chapel Hill. laboratory collection features over 6,000 natural products worldwide, including pure compounds semi-synthetic derivatives. This is most comprehensive fully operational product database Taiwan. review article explores history development NPRL CMUH. We then provide an overview recent applications impact artificial intelligence (AI) new drug discovery. Finally, we examine advanced powerful AI-tools related software to explain how these resources can be utilized research on large-scale data libraries. presents a (R&D) platform that combines AI NPRL. believe this approach will reduce resource wastage enhance capabilities Taiwan's academic industrial sectors biotechnology pharmaceuticals.

Язык: Английский

Процитировано

0