Unlocking the Reactivity of the C-In Bond: Alkyl Indium Reagents as a Source of Radicals Under Photocatalytic Conditions

Chemical Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Generation of organic radicals from organometallic compounds is a key step in metallaphotoredox cross-coupling reactions. The ability organoindium to serve as sources alkyl under light promoted oxidative conditions described. Organoindium reagents were used dual photocatalytic/nickel with aryl bromides. These can be conveniently obtained primary, secondary and tertiary bromides chlorides using novel indium(i) bromide/lithium bromide system. Both steps, the formation organoindiums their are insensitive towards air moisture tolerate wide variety functional groups.

Язык: Английский

Benzothiazolines Acting as Carbanion and Radical Transfer Reagents in Carbon–Carbon Bond Construction

Molecules, Год журнала: 2025, Номер 30(8), С. 1711 - 1711

Опубликована: Апрель 11, 2025

Traditionally employed as hydrogenation reagents, benzothiazolines have emerged versatile carbanion and radical transfer playing a vital role in the construction of various carbon-carbon bonds. The cutting-edge progress photochemistry chemistry prompted study visible light-driven reactions, bringing into vibrant focus. Their chemical processes been uncovered to encompass variety activation mechanisms, with five distinct modes having identified. This work reviews innovative applications donors alkyl or acyl groups, achieving hydroalkylation hydroacylation substitution. By examining their diverse this review highlights potential serving groups for further research development. Moreover, will offer exemplary inspiration synthetic chemists, contributing ongoing evolution utility organic synthesis.

Язык: Английский