Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Май 19, 2025
Photocatalytic multicomponent reactions are at the forefront of organic synthesis. In recent years, dicarbofunctionalization olefins has received significant attention, with nickel serving as a key transition metal catalyst under photochemical conditions. However, achieving regioselective 1,4-alkylarylation dienes alkyl and aryl bromides remains challenging. this work, we present Ni/photoredox dual catalysis approach for alkylarylation dienes, offering mild reaction that eliminates need stochiometric reductants. Broad substrate scope mechanistic investigations presented support proposed mechanism.
Язык: Английский