Wiley Interdisciplinary Reviews Computational Molecular Science, Год журнала: 2024, Номер 14(6)

Опубликована: Ноя. 1, 2024

ABSTRACT Active matters, which consume energy to exert mechanical forces, include molecular motors, synthetic nanomachines, actively propelled bacteria, and viruses. A series of unique phenomena emerge when active matters interact with cellular interfaces. Activity changes the mechanism nanoparticle intracellular delivery, while processes generated in cytoskeleton play a major role membrane protein distribution transport. This review provides comprehensive overview theoretical simulation models used study these nonequilibrium phenomena, offering insights into how activity enhances uptake, influences deformation, governs surface transport dynamics. Furthermore, we explore impact properties, such as fluidity viscosity, on efficiency discuss slippage dynamics rotation behaviors surface. The interplay particles membranes highlights essential processes, potential applications drug delivery nanotechnology. Finally, provide an outlook highlighting significance deeper simulation‐based investigations optimize understand their behavior complex biological environments.

Язык: Английский