Multi-Signal Fluorescent Probe for Simultaneous Differentiation and Imaging of Hg2+, Cys, Hcy, and GSH in Living Cells and Zebrafish

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 137427 - 137427

Опубликована: Янв. 1, 2025

Язык: Английский

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Surface functionalized nanomaterial systems for targeted therapy of endocrine related tumors: a review of recent advancements

Drug Delivery, Год журнала: 2024, Номер 31(1)

Опубликована: Авг. 13, 2024

The application of multidisciplinary techniques in the management endocrine-related cancers is crucial for harnessing advantages multiple disciplines and their coordinated efforts eliminating tumors. Due to malignant characteristics cancer cells, they possess capacity develop resistance traditional treatments such as chemotherapy radiotherapy. Nevertheless, despite diligent endeavors enhance prediction outcomes, overall survival rate individuals afflicted with malignancy remains quite miserable. Hence, it imperative investigate innovative therapy strategies. latest advancements therapeutic tactics have offered novel approaches various endocrine This paper examines nano-drug delivery utilization nanomaterials precise cures through targeted therapy. review provides a thorough analysis potential combined drug strategies treatment thyroid cancer, adrenal gland tumors, pancreatic cancer. objective this study gain deeper understanding current approaches, stimulate development new DDS, improve effectiveness patients these diseases. intracellular uptake pharmaceuticals into cells can be significantly improved implantation synthetic or natural substances nanoparticles, resulting substantial reduction malignancies.

Язык: Английский

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A Fluorescent Probe Containing Triphenylamine‐Benzofuranone Moiety for Detecting Cysteine and Imaging in Living Pulmonary Cells Under Hypercapnia

Luminescence, Год журнала: 2024, Номер 39(10)

Опубликована: Окт. 1, 2024

ABSTRACT In this work, a fluorescent probe TPB‐Cys derived from triphenylamine‐benzofuranone was developed for monitoring the cysteine (Cys) level and imaging in living pulmonary cells under hypercapnia condition. A systematic hypoxia module tried to cover both in‐solution test cellular imaging. The condition did not obviously affect fluorescence response signal during test. at 540 enhanced dose‐dependent enhancement along with increase of Cys concentration. showed advantages including relatively long linear range, high sensitivity, stability, selectivity. With low cyto‐toxicity, achieved endogenous cells. Furthermore, it also realized visualization affection recovered conditions. This work informative accurate diagnosis potential medical techniques.

Язык: Английский

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A Multi-Signal Fluorescent Probe for Simultaneous Differentiation and Imaging of Hg2+, Cys, Hcy and Gsh in Living Cells and Zebrafish

Опубликована: Янв. 1, 2024

Язык: Английский

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