Nanomedicine in Neuroprotection, Neuroregeneration, and Blood–Brain Barrier Modulation: A Narrative Review DOI Creative Commons

Antea Kršek,

Ana Jagodic,

Lara Batičić

и другие.

Medicina, Год журнала: 2024, Номер 60(9), С. 1384 - 1384

Опубликована: Авг. 24, 2024

Nanomedicine is a newer, promising approach to promote neuroprotection, neuroregeneration, and modulation of the blood–brain barrier. This review includes integration various nanomaterials in neurological disorders. In addition, gelatin-based hydrogels, which have huge potential due biocompatibility, maintenance porosity, enhanced neural process outgrowth, are reviewed. Chemical modification these especially with guanidine moieties, has shown improved neuron viability underscores tailored biomaterial design applications. further discusses strategies modulate barrier—a factor critically associated effective delivery drugs central nervous system. These advances bring supportive solutions solving conditions innovative therapies for their treatment. Nanomedicine, as applied neuroscience, presents significant leap forward new therapeutic that might help raise treatment management disorders much better levels. Our aim was summarize current state-of-knowledge this field.

Язык: Английский

Nanotechnology to Overcome Blood–Brain Barrier Permeability and Damage in Neurodegenerative Diseases DOI Creative Commons
Adriana Jiménez, Enrique Estudillo, Mara A. Guzmán‐Ruiz

и другие.

Pharmaceutics, Год журнала: 2025, Номер 17(3), С. 281 - 281

Опубликована: Фев. 20, 2025

The blood–brain barrier (BBB) is a critical structure that maintains brain homeostasis by selectively regulating nutrient influx and waste efflux. Not surprisingly, it often compromised in neurodegenerative diseases. In addition to its involvement these pathologies, the BBB also represents significant challenge for drug delivery into central nervous system. Nanoparticles (NPs) have been widely explored as carriers capable of overcoming this effectively transporting therapies brain. However, their potential directly address ameliorate dysfunction has received limited attention. review, we examine how NPs enhance across treat diseases explore emerging strategies restore integrity vital structure.

Язык: Английский

Процитировано

1
Nanomedicine in Neuroprotection, Neuroregeneration, and Blood–Brain Barrier Modulation: A Narrative Review DOI Creative Commons

Antea Kršek,

Ana Jagodic,

Lara Batičić

и другие.

Medicina, Год журнала: 2024, Номер 60(9), С. 1384 - 1384

Опубликована: Авг. 24, 2024

Nanomedicine is a newer, promising approach to promote neuroprotection, neuroregeneration, and modulation of the blood–brain barrier. This review includes integration various nanomaterials in neurological disorders. In addition, gelatin-based hydrogels, which have huge potential due biocompatibility, maintenance porosity, enhanced neural process outgrowth, are reviewed. Chemical modification these especially with guanidine moieties, has shown improved neuron viability underscores tailored biomaterial design applications. further discusses strategies modulate barrier—a factor critically associated effective delivery drugs central nervous system. These advances bring supportive solutions solving conditions innovative therapies for their treatment. Nanomedicine, as applied neuroscience, presents significant leap forward new therapeutic that might help raise treatment management disorders much better levels. Our aim was summarize current state-of-knowledge this field.

Язык: Английский

Процитировано

3