Recent Advances in Food Safety Detection: Split Aptamer-Based Biosensors Development and Potential Applications

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Ensuring food safety is a shared responsibility across the entire supply chain, encompassing manufacturers, processors, retailers, consumers, and regulatory bodies. However, traditional detection methods have several limitations, including slow processing times, high costs, limited sensitivity, susceptibility to false positives or negatives. These shortcomings underscore urgent need for faster, more accurate, cost-effective technologies. Aptamers aptasensors emerged as promising alternatives. offer advantages over recognition probes due their affinity specificity diverse targets. The enable rapid detection, cost reduction, shelf life extension, minimal batch-to-batch variability, making them highly suitable applications. Detecting small molecules such toxins, antibiotics, pesticides, contaminants, heavy metals remains challenging steric hindrance, nonspecific binding, reduced accuracy. Recent advancements in aptamer technology focused on pre- postmodifications enhance performance. One of most innovations development split aptamers. engineered aptamers, designed operate segments known improved flexibility binding specificity, effectively addressing challenges detecting small-sized This review examines evolution aptamers aptasensors, focusing application that are essential safety. It reported strategies modifying optimizing selected providing details developing approach address unique small-molecule detection. Additionally, recent its integration into aptasensor highlighted, showcasing how these revolutionizing hazards by overcoming limitations methods.

Язык: Английский

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Design and Synthesis of Novel Styrylquinolinium Derivatives for the Treatment of Breast Cancer: Targeting the c-Myc G-Quadruplex

European Journal of Medicinal Chemistry, Год журнала: 2025, Номер 291, С. 117663 - 117663

Опубликована: Апрель 20, 2025

Язык: Английский

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Aptamers capable of simultaneously identifying multiple targets and corresponding applications in medical diagnosis—A review

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143666 - 143666

Опубликована: Апрель 1, 2025

Язык: Английский

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Advancements and Prospects in DNA-Based Bioanalytical Technology for Environmental Toxicant Detection

JACS Au, Год журнала: 2025, Номер unknown

Опубликована: Июнь 2, 2025

Язык: Английский

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