Photodynamic Therapy (PDT) in Drug Delivery: Nano-innovations enhancing treatment outcomes
Health Sciences Review,
Год журнала:
2025,
Номер
unknown, С. 100218 - 100218
Опубликована: Янв. 1, 2025
Язык: Английский
Advances in Photothermal Therapy for Oral Cancer
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(9), С. 4344 - 4344
Опубликована: Май 2, 2025
Oral
cancer
represents
a
critical
global
health
issue,
where
traditional
treatment
modalities
are
often
characterized
by
considerable
adverse
effects
and
suboptimal
effectiveness.
Photothermal
therapy
(PTT)
offers
an
innovative
method
for
tumor
treatment,
leveraging
photothermal
agents
to
convert
light
into
hyperthermia,
ultimately
leading
ablation.
PTT
unique
advantages
in
treating
oral
due
its
superficial
anatomical
location
consequent
accessibility
laser
irradiation.
PTT’s
advantage
is
further
enhanced
capacity
facilitate
drug
release
promote
tissue
regeneration.
Consequently,
the
application
of
has
garnered
widespread
interest
undergone
rapid
development.
This
review
outlines
advances
cancer,
emphasizing
strategies
improve
efficacy
combination
approaches.
The
key
challenges,
including
temperature
control
long-term
biosafety,
discussed
alongside
future
directions.
also
encompasses
role
managing
potentially
malignant
disorders
postoperative
defects,
conditions
intimately
linked
with
cancer.
We
aim
provide
guidance
emerging
research
development
precise
efficient
strategies.
Язык: Английский
Synergistic Cancer Therapies Enhanced by Nanoparticles: Advancing Nanomedicine Through Multimodal Strategies
Pharmaceutics,
Год журнала:
2025,
Номер
17(6), С. 682 - 682
Опубликована: Май 22, 2025
Cancer
remains
a
formidable
global
health
challenge
due
to
its
complex
pathophysiology
and
resistance
conventional
treatments.
In
recent
years,
the
convergence
of
nanotechnology
oncology
has
paved
way
for
innovative
therapeutic
platforms
that
address
limitations
traditional
modalities.
This
review
examines
how
nanoparticle
(NP)-based
strategies
enhance
efficacy
chemotherapy,
radiotherapy,
phototherapy,
immunotherapy,
gene
therapy
by
enabling
targeted
delivery,
controlled
drug
release,
tumor-specific
accumulation
via
enhanced
permeability
retention
(EPR)
effect.
We
discuss
design
functionalization
various
organic,
inorganic,
hybrid
NPs,
highlighting
their
roles
in
improving
pharmacokinetics,
overcoming
multidrug
resistance,
modulating
tumor
microenvironment.
Particular
emphasis
is
placed
on
dual
multimodal
therapies,
such
as
chemo-phototherapy,
chemo-immunotherapy,
gene-radiotherapy,
leverage
carriers
amplify
synergistic
effects,
minimize
systemic
toxicity,
improve
clinical
outcomes.
also
explore
cutting-edge
advances
editing
personalized
nanomedicine,
well
emerging
biological
barriers
immunosuppressive
mechanisms
niche.
Despite
undeniable
promise
nanoparticle-based
cancer
challenges
related
scalable
manufacturing,
regulatory
oversight,
long-term
biocompatibility
must
be
overcome
before
they
can
fully
enter
practice.
By
synthesizing
findings
identifying
key
opportunities
innovation,
this
provides
insight
into
nanoscale
are
propelling
next
generation
precision
oncology.
Язык: Английский
Golden insights for exploring cancer: delivery, from genes to the human body using bimetallic Au/Ag nanostructures
Discover Oncology,
Год журнала:
2025,
Номер
16(1)
Опубликована: Май 25, 2025
Sweeping
contact
with
cancer
continues
to
rise
globally,
which
has
led
advanced
research
on
new
treatment
approaches;
nanotechnology
become
crucial
targeted
therapy.
Within
the
intimate
of
nanomaterials,
Au/Ag
nanostructures
have
emerged
as
highly
attractive
because
their
distinctive
desirable
characteristics
and
prospective
roles
in
diagnosis
well
The
developed
revealed
remarkable
biocompatibility,
optically
recursive
alteration,
magnificently
improved
therapeutic
effects
gold
silver
conjunction
each
other.
This
review
addresses
molecular
systemic
aspects
research,
including
impact
genetic
pathways
use
administration
human
organism.
We
explain
some
related
mechanisms
action,
such
photothermal
therapy
(PTT),
photodynamic
(PDT),
drug
delivery
systems
where
they
display
potential
benefits
towards
offering
a
more
approach
fewer
side
effects.
latest
development
shown
that
prospect
real-time
imaging
biomarker
identification,
owing
this
are
being
viewed
tool
for
individualized
treatment.
However,
there
still
limitations:
challenges
scaling
up,
biological
safety,
bringing
it
clinic.
It
is
therefore
incumbent
upon
these
managements
overcome
hurdles
optimize
impact.
As
result,
current
findings
briefly
reviewed,
directions
discussed
support
revolutionary
role
Язык: Английский