Bacteria Flagella‐Mimicking Polymer Multilayer Magnetic Microrobots
Small Methods,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 21, 2025
Mass
production
of
biomedical
microrobots
demands
expensive
and
complex
preparation
techniques
versatile
biocompatible
materials.
Learning
from
natural
bacteria
flagella,
the
study
demonstrates
a
magnetic
polymer
multilayer
cylindrical
microrobot
that
bestows
controllable
propulsion
upon
an
external
rotating
field
with
uniform
intensity.
The
are
constructed
by
template-assisted
layer-by-layer
technique
subsequent
functionalization
particles
onto
large
opening
microrobots.
Geometric
variables
microrobots,
such
as
diameter
wall
thickness,
can
be
controlled
selection
porous
template
layers
assembly.
perform
through
manipulation
field.
comparative
analysis
movement
behavior
reveals
deformation
may
attributed
to
field,
which
is
similar
bacteria.
influence
actuation
frequency
on
velocity
studied.
Such
provide
novel
concept
develop
rapidly
delivering
drug
therapeutic
agents
for
diverse
practical
uses.
Язык: Английский
Magnetically Driven Hydrogel Microrobots for Targeted Antibiotic Delivery
Chemistry - An Asian Journal,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 22, 2025
Abstract
Precise
targeted
delivery
of
antibiotics
to
infected
sites
is
crucial
for
enhancing
therapeutic
efficacy
and
minimizing
side
effects.
In
this
work,
we
present
magnetic
hydrogel‐based
microrobots
active
antibiotic
achieve
bacterial
elimination.
These
comprise
a
poly(acrylic
acid‐co‐acrylamide)
hydrogel
microspheres
encapsulating
Fe
3
O
4
nanoparticle
chains.
The
scaffold
offers
abundant
spaces
binding
high‐capacity
loading
vancomycin
via
electrostatic
interactions.
embedded
nanochains
enable
propulsion.
Under
rotating
field
(
H
r
t
)),
the
can
actively
deliver
their
swarming
motions,
then
eliminate
bacteria
(e.g.,
Staphylococcus
aureus
)
utilizing
sustainable
release
on
site.
hold
great
promise
as
motile
antibacterial
platform
treat
infectious
diseases.
Язык: Английский