Nature Herbal Medicine‐ Tissue Engineering Strategies for Regulate Cell Homeostasis in Bone Regeneration

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 10, 2025

Abstract Bone fractures, especially large and complex defects, continue to pose significant challenges in the medical field. Current treatments often rely on autografts or allografts for structural support, which can lead problems such as reduced bioactivity, infection risks, potential pathogen transmission. Nature herbal medicine (NHM), including herbs extracts, offers a promising alternative by effectively modulating inflammatory responses, enhancing osteoblast function, inhibiting bone resorption, thereby facilitating fracture repair. However, traditional drug delivery methods NHM encounter interactions, poor tissue distribution, patient compliance. Biomaterials, engineered interact with biological systems, play essential roles repair, mechanical delivery. When used carriers, biomaterials be combined form stable systems that further promote regeneration. Here applications of are reviewed, hydrogels, extracellular vesicles, cement, conjunction regulating homeostasis aiming provide valuable insights guidance future research therapeutic strategies.

Язык: Английский

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Boron-doped silica/chitosan-based elastic three-dimensional sponge scaffold for bone regeneration

Carbohydrate Polymers, Год журнала: 2025, Номер unknown, С. 123491 - 123491

Опубликована: Март 1, 2025

Язык: Английский

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Self-lubrication and enhanced wear and corrosion resistance of calcium silicate hydrate nanostructures on Ti-based micro-arc oxidized coatings

Smart Materials in Manufacturing, Год журнала: 2025, Номер 3, С. 100081 - 100081

Опубликована: Янв. 1, 2025

Язык: Английский

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Enhanced surface hydrophilicity improves osseointegration of titanium implants via integrin-mediated osteoimmunomodulation

Journal of Materials Chemistry B, Год журнала: 2024, Номер unknown

Опубликована: Дек. 10, 2024

The integrin-mediated immunomodulatory effects of hydrophilic titanium modified by non-thermal atmospheric plasma (NTAP), and improved osteogenic responses under this NTAP-created immune microenvironment.

Язык: Английский

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Engineered sonosensitive probiotics extracellular vesicles coating for ultrasound-driven anti-infection and immunoregulation in implant infection treatment

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 158946 - 158946

Опубликована: Дек. 1, 2024

Язык: Английский

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