Gut microbiota in post-acute COVID-19 syndrome: not the end of the story DOI Creative Commons

Yaping An,

Linlin He,

Xin Xu

и другие.

Frontiers in Microbiology, Год журнала: 2024, Номер 15

Опубликована: Дек. 24, 2024

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has led to major global health concern. However, the focus on immediate effects was assumed as tip of iceberg due symptoms following infection, which defined post-acute COVID-19 (PACS). Gut microbiota alterations even after resolution and gastrointestinal are key features PACS. derived metabolites disorders may play a crucial role in inflammatory immune response SARS-CoV-2 infection through gut-lung axis. Diet is one modifiable factors closely related gut COVID-19. In this review, we described reciprocal crosstalk between lung, highlighting participation diet destroying barrier, perturbing metabolism regulating system. Therefore, bolstering beneficial species dietary supplements, probiotics or prebiotics fecal transplantation (FMT) be novel avenue for PACS prevention. This review provides better understanding association long-term consequences COVID-19, indicates modulating dysbiosis potentiality addressing multifaceted condition.

Язык: Английский

Gut microbiota in post-acute COVID-19 syndrome: not the end of the story DOI Creative Commons

Yaping An,

Linlin He,

Xin Xu

и другие.

Frontiers in Microbiology, Год журнала: 2024, Номер 15

Опубликована: Дек. 24, 2024

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has led to major global health concern. However, the focus on immediate effects was assumed as tip of iceberg due symptoms following infection, which defined post-acute COVID-19 (PACS). Gut microbiota alterations even after resolution and gastrointestinal are key features PACS. derived metabolites disorders may play a crucial role in inflammatory immune response SARS-CoV-2 infection through gut-lung axis. Diet is one modifiable factors closely related gut COVID-19. In this review, we described reciprocal crosstalk between lung, highlighting participation diet destroying barrier, perturbing metabolism regulating system. Therefore, bolstering beneficial species dietary supplements, probiotics or prebiotics fecal transplantation (FMT) be novel avenue for PACS prevention. This review provides better understanding association long-term consequences COVID-19, indicates modulating dysbiosis potentiality addressing multifaceted condition.

Язык: Английский

Процитировано

0