Serum untargeted metabolomics analysis of uremic pruritus in patients with various etiologies DOI

Ruizhi Tan,

Lisa X. Xu, Tong Li

и другие.

International Immunopharmacology, Год журнала: 2024, Номер 143, С. 113563 - 113563

Опубликована: Ноя. 12, 2024

Язык: Английский

Cardiovascular Disease and Dialysis: A Review of the Underlying Mechanisms, Methods of Risk Stratification, and Impact of Dialysis Modality Selection on Cardiovascular Outcomes DOI Creative Commons

Trey Richardson,

Martin J. Gardner, Megha Salani

и другие.

Kidney and Dialysis, Год журнала: 2025, Номер 5(1), С. 5 - 5

Опубликована: Янв. 23, 2025

Cardiovascular disease is the leading cause of morbidity and mortality in patients with end-stage kidney (ESKD). To date, no trial has been adequately powered to evaluate effects different dialysis modalities on cardiovascular events or mortality. properly assess risks benefits each modality for individual patients, it crucial understand unique risk factors undergoing dialysis. This review explores existing literature assessment this population. It examines mechanisms contributing increased risk, including volume overload, blood pressure abnormalities, mineral bone disorder, vascular calcification, uremia, anemia, chronic inflammation. Additionally, we discuss data from trials assessing outcomes compare various modalities, in-center hemodialysis, frequent dialysis, nocturnal peritoneal

Язык: Английский

Процитировано

0

Drivers and mechanisms of cognitive decline in chronic kidney disease DOI
Giovambattista Capasso, Casper Franssen, Alessandra F. Perna

и другие.

Nature Reviews Nephrology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 25, 2025

Язык: Английский

Процитировано

0

Gut microbiota-derived indole-3-propionic acid alleviates diabetic kidney disease through its mitochondrial protective effect via reducing ubiquitination mediated-degradation of SIRT1 DOI Creative Commons
Yan Zeng, Man Guo, Qi Wu

и другие.

Journal of Advanced Research, Год журнала: 2024, Номер unknown

Опубликована: Авг. 1, 2024

Gut microbes and their metabolites play crucial roles in the pathogenesis of diabetic kidney disease (DKD). However, which one how specific gut-derived affect progression DKD remain largely unknown.

Язык: Английский

Процитировано

2

Exploring The Impact Of Dialysis On Neurological Conditions: Insights From Biochemical Data In Chronic Kidney Disease DOI Creative Commons

Ahmed Kareem Thamer

Journal of Medical Genetics and Clinical Biology, Год журнала: 2024, Номер 1(3), С. 46 - 59

Опубликована: Апрель 4, 2024

When an individual goes through dialysis in chronic kidney disease, the substances located bodies of patients undergo considerable fluctuations. Creatinine and urea are considered as function indicators. In this regard, is indicator change, creatinine reflects efficiency glomerular filtration. The following data markers that need to be kept on observation under individuals dialysis. goal investigation biochemical parameters ratio pick up can reflect patients’ neurological state To ensure transparency reliability sources, systematic review scientific methodological literature represented electronic databases VHL, Google scholar, SciELO, recent publications from 2014-2023 has been carried out. Development subject had given relationship variables CKD, creatinine, urea. inclusion summary provided. Research stakeholders included studies were associated with compared denatured changes among bio-variable both before after Dialysis. With extracted shown analyzed how treatment impacted CKD regarding changes. Results: lead a great change report persistent disease. Hemodialysis was significant intervention since it influences metabolic values towards normalcy. seen affected much their levels indicated abnormalities organs. Therefore remain valuable that, required for any regular check undergoing treatment. Conclusion: It imperative healthcare providers treating well versed indicators such urea, understand importance patient management. Appropriate timely monitoring these enables professionals initiate prompt adjustments enhance care quality life. Based findings, current demonstrate significance providing insights into management options

Язык: Английский

Процитировано

0

Serum untargeted metabolomics analysis of uremic pruritus in patients with various etiologies DOI

Ruizhi Tan,

Lisa X. Xu, Tong Li

и другие.

International Immunopharmacology, Год журнала: 2024, Номер 143, С. 113563 - 113563

Опубликована: Ноя. 12, 2024

Язык: Английский

Процитировано

0