Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 25, 2024
Comprehensive
Summary
3,3‐Disubstituted
oxindoles,
forming
the
core
of
extensive
bioactive
natural
products
and
drugs,
attract
tremendous
efforts
to
develop
efficient
methods
for
their
preparation.
Here,
a
photocatalyst‐free
approach
synthesis
3,3‐disubstituted
oxindoles
via
substrate‐photosensitive
strategy
under
visible
light
was
successfully
developed.
Preliminary
mechanistic
studies
illustrated
that
isatin‐derived
imines
can
be
directly
excited
by
generate
strong
oxidant
states,
facilitating
subsequent
single‐electron
transfer
(SET)
processes
with
Hantzsch
esters
afford
corresponding
α‐amino
radical
intermediates.
Thus,
these
radicals
promote
Giese
addition
or
radical/radical
cross‐coupling
reactions
furnish
diverse
functionalized
3‐substituted
3‐aminooxindoles
in
high
yields.
Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(31)
Опубликована: Март 28, 2024
Abstract
Photoinduced
aryl
radical
generation
is
a
powerful
strategy
in
organic
synthesis
that
facilitates
the
formation
of
diverse
carbon‐carbon
and
carbon‐heteroatom
bonds.
The
synthetic
applications
photoinduced
complex
compounds,
including
natural
products,
physiologically
significant
molecules,
functional
materials,
have
received
immense
attention.
An
overview
current
developments
production
methods
their
uses
given
this
article.
A
generalized
idea
how
to
choose
reagents
approach
for
radicals
described,
along
with
techniques
associated
mechanistic
insights.
Overall,
article
offers
critical
assessment
results
as
well
selection
reaction
parameters
specific
context
cascades,
cross‐coupling
reactions,
functionalization,
selective
C−H
functionalization
substrates.
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(10), С. 4926 - 4975
Опубликована: Янв. 1, 2024
In
search
for
the
perfect
wave(length).
This
review
is
dedicated
to
recent
efforts
in
development
of
visible
light
driven
photochemical
strategies
occurring
coloured
organic
compounds.
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
366(2), С. 168 - 182
Опубликована: Дек. 16, 2023
Abstract
Photoinduced
chemical
transformations
have
become
a
promising
aspect
of
organic
synthesis.
This
review
focuses
on
the
recent
advancements
in
harnessing
photoinduced
processes
for
formation
carbon‐chalcogen
(C−O,
C−S,
C−Se,
and
C−Te)
bonds
under
catalyst‐free
conditions.
These
pathways
typically
involve
either
radical
mechanism
or
creation
electron‐donor‐acceptor
(EDA)
complexes.
The
explores
intricacies
underlying
mechanisms,
discusses
limitations,
evaluates
applicability
various
methodologies
this
field.
Notably,
photocatalyst
transition
metal‐free
photochemical
reactions
offer
effective
alternatives
to
enhance
sustainability
research
area.
Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
19(14)
Опубликована: Май 8, 2024
The
beginning
of
photochemical
reactions
revolutionized
synthetic
chemistry
through
sustainable
practices.
This
review
explores
cutting-edge
developments
in
leveraging
light-induced
processes
for
generating
cascaded
C-C
and
C-hetero
bonds
without
catalysts.
Significantly,
catalyst-free
photoinduced
methodologies
have
garnered
considerable
attention,
especially
the
creation
varied
heterocyclic
frameworks
drug
design
synthesis
natural
products.
article
delves
into
underlying
mechanisms,
addresses
limitations,
evaluates
various
methodologies,
emphasizing
potential
photocatalyst
transition
metal-free
to
enhance
sustainability.
Divided
two
sections,
it
covers
recent
strides
C-heteroatom
multiple
bond
formation
reactions.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 31, 2023
Abstract
Achieving
high
molecular
complexity
can
be
not
trivial,
but
the
exploitation
of
domino
reactions
provides
an
atom‐
and
step‐economical
method
to
reach
this
target.
Over
past
decades,
a
lot
efforts
have
been
put
on
development
photocatalytic
cascades
employing
both
metal‐based
purely
organic
catalysts.
Despite
effectiveness
these
protocols,
catalyst‐
additive‐free
light‐induced
are
gaining
momentum
thank
their
efficiency,
operational
simplicity
sustainability.
The
increasing
number
papers
published
field
in
last
years
is
proof
appeal
transformations.
In
Review,
we
discuss
multicomponent
mediated
by
light
with
focus
photocatalyst‐
processes.
most
recent
advances
synthesis
complex
nitrogen‐,
oxygen‐,
sulphur‐
selenium‐heterocycles
together
analysed
emphasis
experimental
mechanistic
studies.
Chemistry - An Asian Journal,
Год журнала:
2023,
Номер
18(21)
Опубликована: Сен. 25, 2023
The
increasing
global
warming
concerns
have
propelled
a
surge
in
the
demand
for
sustainable
energy
sources
within
domain
of
synthetic
organic
chemistry.
A
particularly
prominent
area
research
has
been
development
mild
strategies
generating
heterocyclic
compounds.
Heterocyclic
compounds
containing
boron
notably
risen
to
prominence
as
pivotal
reagents
myriad
transformations,
showcasing
their
wide-ranging
applicability.
This
comprehensive
review
is
aimed
at
collecting
literature
pertaining
borylation
reactions
induced
by
light,
specifically
focusing
on
photocatalyst-free
and
transition
metal-free
methodologies.
central
emphasis
delving
into
selective
mechanistic
investigations.
amalgamation
analysis
these
insights
elucidate
substantial
potential
inherent
eco-friendly
approaches
synthesizing
compounds,
thus
propelling
landscape
Alkylboron
reagents
have
historically
posed
significant
challenges
in
transition-metal
catalysis,
primarily
due
to
the
comparable
electronegativities
of
carbon
(C)
and
boron
(B),
which
results
weakly
polarized
C-B
bonds
that
hinder
efficient
transmetalation.
Additionally,
propensity
for
β-hydride
elimination
further
complicates
transmetalation
process,
limiting
their
applicability
synthetic
transformations.
In
this
study,
we
present
a
groundbreaking
transition-metal-free
strategy
intramolecular
coupling
C(sp3)-B
with
C(sp2)-H
bonds.
This
innovative
approach
operates
under
mild
reaction
conditions,
exhibits
exceptional
functional
group
compatibility,
enables
construction
diverse
polycyclic
frameworks.
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
22(5), С. 869 - 893
Опубликована: Дек. 25, 2023
The
photochemical
action
of
arylazo
sulfones
under
visible
light
irradiation
has
recently
gained
considerable
attention
for
the
construction
carbon-carbon
and
carbon-heteroatom
bonds
in
organic
synthesis.
inherent
dyedauxiliary
group
(-N
Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(67)
Опубликована: Авг. 13, 2024
Abstract
Using
organic
dyes
as
photocatalysts
is
an
innovative
approach
to
photocatalytic
transformations.
These
offer
advantages
such
widespread
availability,
adaptable
absorption
properties,
and
diverse
chemical
structures.
Recent
progress
has
led
the
development
of
that
can
utilize
visible
light
modify
chemically
inert
C−H
bonds.
catalysts
are
sustainable,
selective,
versatile,
enabling
mild
reactions,
late‐stage
functionalization,
various
transformations
in
line
with
green
chemistry
principles.
As
photoredox
chemistry,
they
contribute
efficient
environmentally
friendly
synthetic
pathways.
Acridinium‐based
have
proved
valuable
transformative
reactions
under
conditions.
This
review
emphasizes
their
features,
frameworks,
applications
modifying
complex
molecules.
It
provides
overview
recent
advancements
use
acridinium‐based
for
bond
functionalization
without
need
transition
metals,
showcasing
potential
expedite
new
molecules
igniting
excitement
about
prospects
this
research
field.
