Journal of the American Chemical Society, Год журнала: 2025, Номер unknown

Опубликована: Май 26, 2025

Here, we report a photo- and copper-catalyzed enantioselective oxidation of benzylic C(sp3)-H bonds using N-hydroxyphthalimide as the oxygenated reagent. The reaction proceeds under mild conditions does not require excess substrates or oxidants. products can be readily transformed into chiral alcohols hydroxylamines. Preliminary mechanism studies suggest that via free radical mechanism.

Язык: Английский