Artificial Molecular Ratchets: Tools Enabling Endergonic Processes
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
62(47)
Опубликована: Авг. 7, 2023
Abstract
Non‐equilibrium
chemical
systems
underpin
multiple
domains
of
contemporary
interest,
including
supramolecular
chemistry,
molecular
machines,
prebiotic
and
energy
transduction.
Experimental
chemists
are
now
pioneering
the
realization
artificial
that
can
harvest
away
from
equilibrium.
In
this
tutorial
Review,
we
provide
an
overview
ratchets:
mechanisms
enabling
absorption
environment.
By
focusing
on
mechanism
type—rather
than
application
domain
or
source—we
offer
a
unifying
picture
seemingly
disparate
phenomena,
which
hope
will
foster
progress
in
fascinating
science.
Язык: Английский
Artificial Molecular Ratchets: Tools Enabling Endergonic Processes
Angewandte Chemie,
Год журнала:
2023,
Номер
135(47)
Опубликована: Авг. 7, 2023
Abstract
Non‐equilibrium
chemical
systems
underpin
multiple
domains
of
contemporary
interest,
including
supramolecular
chemistry,
molecular
machines,
prebiotic
and
energy
transduction.
Experimental
chemists
are
now
pioneering
the
realization
artificial
that
can
harvest
away
from
equilibrium.
In
this
tutorial
Review,
we
provide
an
overview
ratchets:
mechanisms
enabling
absorption
environment.
By
focusing
on
mechanism
type—rather
than
application
domain
or
source—we
offer
a
unifying
picture
seemingly
disparate
phenomena,
which
hope
will
foster
progress
in
fascinating
science.
Язык: Английский
Power Strokes in Molecular Motors: Predictive, Irrelevant, or Somewhere in Between?
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 20, 2024
For
several
decades,
molecular
motor
directionality
has
been
rationalized
in
terms
of
the
free
energy
conformations
visited
before
and
after
takes
a
step,
so-called
power
stroke
mechanism
with
analogues
macroscopic
engines.
Despite
theoretical
experimental
demonstrations
its
flaws,
language
is
quite
ingrained,
some
communities
still
value
intuition.
By
building
catalysis-driven
into
simulated
numerical
experiments,
we
here
systematically
report
on
how
responds
when
modified
accordingly
to
We
confirm
that
generally
does
not
predict
directionality.
Nevertheless,
simulations
illustrate
relative
stability
should
be
included
as
potential
design
element
adjust
directional
bias.
Though
strokes
are
formally
unimportant
for
determining
directionality,
show
practical
attempts
alter
have
side
effects
can
fact
The
change
bias
align
what
intuition
would
suggested,
offering
explanation
why
flawed
retain
apparent
utility
engineering
specific
systems.
Язык: Английский
Microfluidic and impedance analysis of rosemary essential oil: implications for dental health
BioMedical Engineering OnLine,
Год журнала:
2024,
Номер
23(1)
Опубликована: Ноя. 4, 2024
Abstract
Background
Oral
health
is
closely
linked
to
systemic
conditions,
particularly
non-communicable
diseases
(NCDs),
which
can
exacerbate
oral
issues.
Essential
oils
(EOs)
have
emerged
as
potential
alternatives
for
due
their
antibacterial,
anti-inflammatory,
and
antioxidant
properties.
Among
these,
rosemary
essential
oil
(REO)
shows
promise
its
various
biological
activities.
This
study
investigates
the
of
REO
in
dental
applications
using
microfluidic
devices
electrochemical
impedance
spectroscopy
(EIS)
analyze
electrical
properties
artificial
saliva
(AS)
mixtures.
Results
The
demonstrated
significant
variations
across
different
concentrations
mixtures
with
AS.
Higher
was
observed
mixtures,
at
lower
frequencies,
indicating
distinct
compared
pure
influenced
by
concentration,
a
1%
solution
showing
higher
than
4%
solution,
possibly
micelle
formation
changes
dielectric
Additionally,
enabled
precise
control
over
fluid
interactions
real-time
monitoring,
offering
valuable
insights
into
REO's
behavior
simulated
environment.
data
differences
REO–AS
highlighting
critical
care
applications.
Conclusions
Rosemary
exhibits
unique
properties,
making
it
promising
candidate
applications,
preventing
treating
diseases.
Microfluidic
enhance
accuracy
reliability
studying
AS,
providing
robust
platform
future
research.
findings
suggest
that
could
be
effectively
incorporated
products,
natural
alternative
combating
pathogens,
reducing
inflammation,
protecting
against
oxidative
stress.
Future
research
should
focus
on
clinical
trials
validate
these
explore
synergistic
effects
other
oils.
Язык: Английский