A scoping review of human pathogens detected in untreated human wastewater and sludge DOI Creative Commons
Tricia Corrin, Prakathesh Rabeenthira, Kaitlin M. Young

и другие.

Journal of Water and Health, Год журнала: 2024, Номер 22(2), С. 436 - 449

Опубликована: Янв. 16, 2024

Abstract Wastewater monitoring is an approach to identify the presence or abundance of pathogens within a population. The objective this scoping review (ScR) was and characterize research on human antimicrobial resistance detected in untreated wastewater sludge. A search conducted up March 2023 standard ScR methodology followed. This included 1,722 articles, which 56.5% were published after emergence COVID-19. Viruses bacteria commonly investigated, while protozoa, helminths, fungi infrequent. Articles prior 2019 dominated by transmitted through fecal–oral waterborne pathways, whereas more recent articles have explored detection other pathways such as respiratory vector-borne. There variation sampling, samples, sample processing across studies. current evidence suggests that could be applied range public health tool detect emerging pathogen understand burden spread disease inform decision-making. Further development refinement methods interpret signals for different prioritized are needed develop standards when, why, how monitor effectively.

Язык: Английский

Wastewater-based monitoring could help guide responses to the USA opioid epidemic DOI Open Access
Fahad Ahmed, Jake O’Brien, Aparna Keshaviah

и другие.

Nature Water, Год журнала: 2023, Номер 1(5), С. 401 - 404

Опубликована: Май 18, 2023

Язык: Английский

Процитировано

15
Identifying trends in SARS-CoV-2 RNA in wastewater to infer changing COVID-19 incidence: Effect of sampling frequency DOI Creative Commons
Elana M. G. Chan, Lauren C. Kennedy, Marlene K. Wolfe

и другие.

PLOS Water, Год журнала: 2023, Номер 2(4), С. e0000088 - e0000088

Опубликована: Апрель 6, 2023

SARS-CoV-2 RNA concentrations in wastewater solids and liquids are correlated with reported incident COVID-19 cases. Reporting of cases has changed dramatically the availability at-home antigen tests. Wastewater monitoring therefore represents an objective tool for continued occurrence. One important use case data is identifying when there sustained changes or trends concentrations. Such information can be used to inform public health messaging, testing, vaccine resources. However, limited research on best approaches data. To fill this knowledge gap, we applied three trend analysis methods (relative strength index (RSI), percent change (PC), Mann-Kendall (MK) test) daily measurements from a treatment plant characterize trends. Because not common programs, also conducted downsampling determine minimum sampling frequency necessary capture identified using “gold standard” The PC MK test appear perform similarly better than RSI terms first detecting increasing decreasing 14-day look-back period, so only considered analysis. Using acceptable sensitivity specificity cutoff 0.5, found that 4 samples/week 5 detect by method, respectively. If higher needed, then more samples per week would needed. Public officials adopt these recommendations programs aimed at providing how changing contributing communities.

Язык: Английский

Процитировано

14
Wastewater surveillance could serve as a pandemic early warning system for COVID‐19 and beyond DOI

Pallavi Gahlot,

Kelly D. Alley, Sudipti Arora

и другие.

Wiley Interdisciplinary Reviews Water, Год журнала: 2023, Номер 10(4)

Опубликована: Май 8, 2023

Abstract Wastewater‐based surveillance can be used as an early warning system to identify COVID‐19 outbreaks because the viral load observed in sewage before it is clinically verified. Wastewater of SARS‐CoV‐2 trace transmission dynamics infection communities when using scale a wastewater diversion and treatment system. Using this detection method help protect human health mitigate socio‐economic losses. It quantify epidemiological data given population real‐time circumvent need for other indicators. There are challenges technique areas with underdeveloped sewerage infrastructure. especially case developing nations where uniform protocols lacking, heterogeneous environmental operational conditions. This article explains importance wastewater‐based SARS‐CoV‐2. lays out most recent methodological approaches detecting municipal outlines main associated epidemiology (WBE). The includes study work across India demonstrate how nation manages research locational challenges. socio‐economic, ethical, policy dimensions WBE also discussed. categorized under: Engineering Water > Water, Health, Sanitation Sustainable Methods

Язык: Английский

Процитировано

14
Separating signal from noise in wastewater data: An algorithm to identify community-level COVID-19 surges in real time DOI Creative Commons
Aparna Keshaviah,

Ian Huff,

Xindi C. Hu

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2023, Номер 120(31)

Опубликована: Июль 25, 2023

Wastewater monitoring has provided health officials with early warnings for new COVID-19 outbreaks, but to date, no approach been validated distinguish signal (sustained surges) from noise (background variability) in wastewater data alert the need heightened public response. We analyzed 62 wk of 19 sites participating North Carolina Monitoring Network characterize metrics around Delta and Omicron surges. found that identified outbreaks 4 5 d before case (reported on earlier symptom start date or test collection date), average. At most sites, correlations between were similar regardless how concentrations normalized whether calculated county-level sewershed-level cases, suggesting may not geospatially align sewershed boundaries gain insights into disease transmission. Although trend lines captured clear differences versus surge trajectories, single metric (detectability, percent change, flow-population viral concentrations) reliably signaled when these surges started. After iteratively examining different combinations three metrics, we developed Covid-SURGE (Signaling Unprecedented Rises Groupwide Exposure) algorithm, which identifies unprecedented signals data. With a true positive rate 82%, false 7%, strong performance during both small large our algorithm provides an automated way flag community-level real time.

Язык: Английский

Процитировано

13
A scoping review of human pathogens detected in untreated human wastewater and sludge DOI Creative Commons
Tricia Corrin, Prakathesh Rabeenthira, Kaitlin M. Young

и другие.

Journal of Water and Health, Год журнала: 2024, Номер 22(2), С. 436 - 449

Опубликована: Янв. 16, 2024

Abstract Wastewater monitoring is an approach to identify the presence or abundance of pathogens within a population. The objective this scoping review (ScR) was and characterize research on human antimicrobial resistance detected in untreated wastewater sludge. A search conducted up March 2023 standard ScR methodology followed. This included 1,722 articles, which 56.5% were published after emergence COVID-19. Viruses bacteria commonly investigated, while protozoa, helminths, fungi infrequent. Articles prior 2019 dominated by transmitted through fecal–oral waterborne pathways, whereas more recent articles have explored detection other pathways such as respiratory vector-borne. There variation sampling, samples, sample processing across studies. current evidence suggests that could be applied range public health tool detect emerging pathogen understand burden spread disease inform decision-making. Further development refinement methods interpret signals for different prioritized are needed develop standards when, why, how monitor effectively.

Язык: Английский

Процитировано

5